DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Taz and TAZ1

DIOPT Version :9

Sequence 1:	NP_477432.3	Gene:	Taz / 36405	FlyBaseID:	FBgn0026619	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_015466.1	Gene:	TAZ1 / 856262	SGDID:	S000006344	Length:	381	Species:	Saccharomyces cerevisiae

Alignment Length:	324	Identity:	85/324 - (26%)
Similarity:	141/324 - (43%)	Gaps:	83/324 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 FPRLRNPSKFWYVVSQFVVSAVGIFSKVVLMFLNKPRVYNRERL---IQLITKRPKGIPLVTVSN 187
            :|| |:|  .|..:|..........||::|......::...|:|   ::...:..:|  |:||.|
Yeast    17 YPR-RSP--LWRFLSYSTSLLTFGVSKLLLFTCYNVKLNGFEKLETALERSKRENRG--LMTVMN 76

  Fly   188 HYSCFDDPGLWGCLPLGIVCNTYKIRWSMAAHDICFTNKLHSLFFMFGKCIPVVR-GIGVYQDAI 251
            |.|..|||.:|..||..:..:...||||:.||:|||.||..:.||..|:.:...| |:|.:|.:|
Yeast    77 HMSMVDDPLVWATLPYKLFTSLDNIRWSLGAHNICFQNKFLANFFSLGQVLSTERFGVGPFQGSI 141

  Fly   252 NLCI-----------------------EKA-------ALGHWIHVFPEGKV-----NMDKEELRL 281
            :..|                       :||       :...|:||:|||.|     ..:......
Yeast   142 DASIRLLSPDDTLDLEWTPHSEVSSSLKKAYSPPIIRSKPSWVHVYPEGFVLQLYPPFENSMRYF 206

  Fly   282 KWGVGRIIYESPKIPIILPMWHEGM---------DDLLPNVEPYVIQRGKQVTLNVGQPLDLNDF 337
            |||:.|:|.|:.|.||::|::..|.         |.:...:.|.  ..|.::.:.:|.|  |||.
Yeast   207 KWGITRMILEATKPPIVVPIFATGFEKIASEAVTDSMFRQILPR--NFGSEINVTIGDP--LNDD 267

  Fly   338 ILDLKKRQ-------VPEPTARKLITDKI---QEAFRDLRA---------------ETEKLHRE 376
            ::|..:::       ..:|.....::|::   :|| :|||:               |..||.||
Yeast   268 LIDRYRKEWTHLVEKYYDPKNPNDLSDELKYGKEA-QDLRSRLAAELRAHVAEIRNEVRKLPRE 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Taz	NP_477432.3	LPLAT_AGPAT-like	153..360	CDD:153251	67/264 (25%)
TAZ1	NP_015466.1	LPLAT_AGPAT-like	41..282	CDD:153251	65/246 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341775
Domainoid	1	1.000	82	1.000	Domainoid score	I1971
eggNOG	1	0.900	-	-		E1_KOG2847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37264
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004731
OrthoInspector	1	1.000	-	-		oto100317
orthoMCL	1	0.900	-	-		OOG6_103216
Panther	1	1.100	-	-	LDO	PTHR12497
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3957
SonicParanoid	1	1.000	-	-		X3327
TreeFam	1	0.960	-	-
	12	11.730