Sequence 1: | NP_610817.1 | Gene: | Mos / 36404 | FlyBaseID: | FBgn0033773 | Length: | 364 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001341859.1 | Gene: | RIPK1 / 8737 | HGNCID: | 10019 | Length: | 671 | Species: | Homo sapiens |
Alignment Length: | 383 | Identity: | 94/383 - (24%) |
---|---|---|---|
Similarity: | 143/383 - (37%) | Gaps: | 99/383 - (25%) |
- Green bases have known domain annotations that are detailed below.
Fly 3 DLLLNTPKRK--QLLKDGPPVPTRCQVLGRGAYGTVFKAIYRDRSVAV-KIIRAQAASTLHN--- 61
Fly 62 --ESHLLN-LEHRNIVRLL-KLESAADFGLVIMECPRGQSLQRIVDTLALPLMHRVLITLDVVAA 122
Fly 123 LRYCHSQNVLHLDVKPTNILVALGTKSSITCNSSKIKVKRSYICKLCDFGSSIEMGEFCAWQE-- 185
Fly 186 ----------PSVAK---GTLRYMSPEALRSDTL--TEASDIYSLGITMWQLQARRLPYHTLDCN 235
Fly 236 ETIAYQVVKHELRPD-----NYHQLKILALDSPIDCDWDLAHESTANVICRRANTSARRNL---- 291
Fly 292 -SLDPSY------TVGRDLK--KKRHRNRLA-------LHFDSPAPEGSACSESAYSQ 333 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Mos | NP_610817.1 | STKc_Mos | 19..298 | CDD:270881 | 73/319 (23%) |
S_TKc | 26..257 | CDD:214567 | 64/260 (25%) | ||
RIPK1 | NP_001341859.1 | STKc_RIP1 | 23..290 | CDD:270929 | 72/304 (24%) |
Interaction with SQSTM1. /evidence=ECO:0000269|PubMed:10356400 | 290..582 | 15/51 (29%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 331..354 | 5/10 (50%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 389..458 | ||||
RIP homotypic interaction motif (RHIM). /evidence=ECO:0000269|PubMed:11734559, ECO:0000269|PubMed:29681455 | 531..547 | ||||
Death_RIP1 | 583..668 | CDD:260048 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E2759_KOG0192 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |