DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mos and RIPK4

DIOPT Version :9

Sequence 1:NP_610817.1 Gene:Mos / 36404 FlyBaseID:FBgn0033773 Length:364 Species:Drosophila melanogaster
Sequence 2:NP_065690.2 Gene:RIPK4 / 54101 HGNCID:496 Length:784 Species:Homo sapiens


Alignment Length:368 Identity:76/368 - (20%)
Similarity:124/368 - (33%) Gaps:139/368 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 TRCQVLGRGAYGTVFKA--IYRDRSVAVKIIRAQAASTLHNESHLLNLEHRNIVRLL----KLES 81
            |..:.:|.|.:|.|:|.  ::....:|:|.            |..|:::.|..:.||    |:|.
Human    23 TGWEKVGSGGFGQVYKVRHVHWKTWLAIKC------------SPSLHVDDRERMELLEEAKKMEM 75

  Fly    82 A------ADFGL------VIMECPRGQSLQRIVDTLALP--LMHRVLITLDVVAALRYCHSQNVL 132
            |      ..:|:      ::||.....||::::.:..||  |..|::....|.....:|.:..:|
Human    76 AKFRYILPVYGICREPVGLVMEYMETGSLEKLLASEPLPWDLRFRIIHETAVGMNFLHCMAPPLL 140

  Fly   133 HLDVKPTNILVALGTKSSITCNSSKIKVKRSYICKLCDFG----------SSIEM-GEFCAWQEP 186
            |||:||.|||                 :...|..|:.|||          ..:.| |.|      
Human   141 HLDLKPANIL-----------------LDAHYHVKISDFGLAKCNGLSHSHDLSMDGLF------ 182

  Fly   187 SVAKGTLRYMSPEALR--SDTLTEASDIYSLGITMWQLQARRLPYHTLDCNETIAYQVVKHELRP 249
                ||:.|:.||.:|  |.......|:||..|.:|.:..::.|:........|..:|||     
Human   183 ----GTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMVKVVK----- 238

  Fly   250 DNYHQLKILALDSPIDCDWDLAHESTANVICRRANTSARRNLSLDPSYTVGRDLKKKRHRNRLAL 314
                                 .|......:||.                          |.|   
Human   239 ---------------------GHRPELPPVCRA--------------------------RPR--- 253

  Fly   315 HFDSPAPEGSACSESAYSQLYKSCWVSAPELRLSSIQLKHELE 357
                      |||.  ..:|.:.||...|.:|.:..::..|.|
Human   254 ----------ACSH--LIRLMQRCWQGDPRVRPTFQEITSETE 284

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MosNP_610817.1 STKc_Mos 19..298 CDD:270881 64/307 (21%)
S_TKc 26..257 CDD:214567 60/263 (23%)
RIPK4NP_065690.2 STKc_RIP4_like 25..290 CDD:270927 75/366 (20%)
STYKc 26..279 CDD:214568 73/358 (20%)
ANK 413..524 CDD:238125
ANK repeat 437..468 CDD:293786
Ank_2 442..534 CDD:289560
ANK repeat 470..501 CDD:293786
ANK 471..589 CDD:238125
ANK repeat 503..534 CDD:293786
Ank_2 508..600 CDD:289560
ANK repeat 536..567 CDD:293786
ANK repeat 569..600 CDD:293786
ANK 598..723 CDD:238125
ANK repeat 603..634 CDD:293786
Ank_2 608..699 CDD:289560
ANK repeat 636..667 CDD:293786
ANK repeat 669..699 CDD:293786
Ank_2 674..764 CDD:289560
ANK 729..>764 CDD:238125
ANK repeat 734..764 CDD:293786
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0192
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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