DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mos and Map3k9

DIOPT Version :9

Sequence 1:	NP_610817.1	Gene:	Mos / 36404	FlyBaseID:	FBgn0033773	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_017170611.1	Gene:	Map3k9 / 338372	MGIID:	2449952	Length:	1120	Species:	Mus musculus

Alignment Length:	367	Identity:	80/367 - (21%)
Similarity:	135/367 - (36%)	Gaps:	118/367 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PPVP---------TRCQVLGRGAYGTVFKAIYRDRSVAVKIIR-------AQAASTLHNESHLL- 66
            ||:.         |..:::|.|.:|.|::|.:....||||..|       :|....:..|:.|.
Mouse   125 PPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWAGDEVAVKAARHDPDEDISQTIENVRQEAKLFA 189

  Fly    67 NLEHRNIVRL----LKLESAADFGLVIMECPRGQSLQRIVDTLALPLMHRVLITLDVVAALRYCH 127
            .|:|.||:.|    ||..:..    ::||..||..|.|::....:|....|...:.:...:.|.|
Mouse   190 MLKHPNIIALRGVCLKEPNLC----LVMEFARGGPLNRVLSGKRIPPDILVNWAVQIARGMNYLH 250

  Fly   128 SQ---NVLHLDVKPTNILVALGTKSSITCNSSKIKVKRSYICKLCDFGSSIEMGEFCAWQEPS-- 187
            .:   .::|.|:|.:|||:....::....|.         |.|:.|||.:.|      |...:
Mouse   251 DEAIVPIIHRDLKSSNILILQKVENGDLSNK---------ILKITDFGLARE------WHRTTKM 300

  Fly   188 VAKGTLRYMSPEALRSDTLTEASDIYSLGITMWQLQARRLPYHTLDCNETIAYQVVKHELRPDNY 252
            .|.||..:|:||.:|:...::.||::|.|:.:|:|....:|:..:| ...:||.|.
Mouse   301 SAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGID-GLAVAYGVA--------- 355

  Fly   253 HQLKILALDSPIDCDWDLAHESTANVICRRANTSARRNLSLDPSYTVGRDLKKKRHRNRLALHFD 317
                                                                    .|:|||...
Mouse   356 --------------------------------------------------------MNKLALPIP 364

  Fly   318 SPAPEGSACSESAYSQLYKSCWVSAPELRLSSIQLKHELEFI 359
            |..||       .:::|.:.||...|..|.|...:..:|..|
Mouse   365 STCPE-------PFAKLMEDCWNPDPHSRPSFTSILDQLTTI 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mos	NP_610817.1	STKc_Mos	19..298	CDD:270881	65/304 (21%)
Mos	NP_610817.1	S_TKc	26..257	CDD:214567	62/247 (25%)
Map3k9	XP_017170611.1	SH3_MLK1-3	49..106	CDD:212992
Map3k9	XP_017170611.1	STKc_MLK1	130..399	CDD:271047	77/360 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810