DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mos and LIMK1

DIOPT Version :9

Sequence 1:	NP_610817.1	Gene:	Mos / 36404	FlyBaseID:	FBgn0033773	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_511139.2	Gene:	LIMK1 / 32207	FlyBaseID:	FBgn0283712	Length:	1257	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	58/247 - (23%)
Similarity:	96/247 - (38%)	Gaps:	74/247 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LGRGAYGTVFKAIYRDRSVAVKIIR------AQAASTLHNESHLLN-LEHRNIVRLL-------K 78
            ||.|.:|.|||..:| :|..|.:::      .:|......|..:|. |:||::::.:       |
  Fly   407 LGEGFFGKVFKVTHR-QSGEVMVLKELHRADEEAQRNFIKEVAVLRLLDHRHVLKFIGVLYKDKK 470

  Fly    79 LESAADFGLVIMECPRGQSLQRIVDTLA--LPLMHRVLITLDVVAALRYCHSQNVLHLDVKPTNI 141
            |.       ::.|...|..|:.::...|  ||...||.:..|:...:.|.||.|::|.|:...|.
  Fly   471 LH-------MVTEYVAGGCLKELIHDPAQVLPWPQRVRLARDIACGMSYLHSMNIIHRDLNSMNC 528

  Fly   142 LVALGTKSSITCNSSKIKVKRSYICKLCDFG--SSIE-------------MGEFCAWQEPSVAKG 191
            ||               :..||.|  :.|||  .|::             .|.......|....|
  Fly   529 LV---------------REDRSVI--VADFGLARSVDAPRLPSGNMTPGGYGSGANSDAPMSPSG 576

  Fly   192 TLR------------------YMSPEALRSDTLTEASDIYSLGITMWQLQAR 225
            |||                  :|:||.::.....|..|::|.||.:.::..|
  Fly   577 TLRRSKSRQRRQRYTVVGNPYWMAPEMMKGLKYDEKVDVFSFGIMLCEIIGR 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mos	NP_610817.1	STKc_Mos	19..298	CDD:270881	58/247 (23%)
Mos	NP_610817.1	S_TKc	26..257	CDD:214567	58/247 (23%)
LIMK1	NP_511139.2	LIM1_LIMK	33..88	CDD:188750
		LIM2_LIMK	95..148	CDD:188751
		PDZ_signaling	172..271	CDD:238492
		STKc_LIMK	407..693	CDD:271056	58/247 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445219
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930