DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mos and Ripk1

DIOPT Version :9

Sequence 1:	NP_610817.1	Gene:	Mos / 36404	FlyBaseID:	FBgn0033773	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001100820.1	Gene:	Ripk1 / 306886	RGDID:	1310158	Length:	658	Species:	Rattus norvegicus

Alignment Length:	234	Identity:	62/234 - (26%)
Similarity:	101/234 - (43%)	Gaps:	46/234 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LGRGAYGTVFKAIYRDRSVAV--KII----RAQAASTLHNESHLLN-LEHRNIVRLLK-LESAAD 84
            |..|.:|.|....:|.....:  |:.    ||:....|..|..::: |.|..:|:||. :....:
  Rat    23 LDSGGFGKVSLCFHRTHGFVILKKVYTGPNRAEYNEALLEEGKMMHRLRHDRVVKLLGIIIEEGN 87

  Fly    85 FGLVIMECPRGQSLQRIVDTLALPLMHRVLITLDVVAALRYCHSQNVLHLDVKPTNILVALGTKS 149
            :.||:....:|..:..:....::||..:..|.::::..:.|.|.:.|:|.|:||.|||
  Rat    88 YSLVMEYMEQGNLMHVLKTKESVPLSVKGRIIVEIIEGMHYLHDEGVIHKDLKPENIL------- 145

  Fly   150 SITCNSSKIKVKRSYICKLCDFGSSIEMGEFCAW------------QEPSVAK---GTLRYMSPE 199
                      |.|.:..|:.|.|    :..|..|            :..||.|   |||.||:||
  Rat   146 ----------VDRDFHIKIADLG----VASFKTWSKLTKEEHNKQREASSVTKKNGGTLYYMAPE 196

  Fly   200 ALR--SDTLTEASDIYSLGITMWQLQARRLPYHTLDCNE 236
            .|.  :...||.||:||..|.:|.:.|.:.||..:.|.|
  Rat   197 HLTDINTKPTEKSDVYSFAIVLWAIFANKEPYENVICTE 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mos	NP_610817.1	STKc_Mos	19..298	CDD:270881	62/234 (26%)
Mos	NP_610817.1	S_TKc	26..257	CDD:214567	62/234 (26%)
Ripk1	NP_001100820.1	PKc_like	23..290	CDD:419665	62/234 (26%)
Ripk1	NP_001100820.1	Death_RIP1	570..655	CDD:260048
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900