Protein Alignment GLS and glsA

DIOPT Version :10

• Sequence 1: NP_001163129.1
• Gene: GLS / 36396
• FlyBaseID: FBgn0261625
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: NP_415018.1
• Gene: glsA / 946187
• ECOCYCID: G6261
• Length: 310
• Species: Escherichia coli
• Alignment Length: 324
• Identity: 108/324 - (33%)
• Similarity: 165/324 - (50%)
• Gaps: 34/324 - (10%)

  Fly   202 DFTSFVKDIEDIYNRCKTNTLGKLADYIPQLARYNPDSWGLSICTIDGQRFSIGDVDVPFTLQSC 266
            |.....:.::..|.:..:...|:.|||||.||........::|.|.||..:|.||.|..|.|:|.
E. coli     3 DANKLQQAVDQAYTQFHSLNGGQNADYIPFLANVPGQLAAVAIVTCDGNVYSAGDSDYRFALESI 67

  Fly   267 SKPLTYAIALEKLGPKVVHSYVGQEPSGRNFNELVLDQ--NKKPHNPMINAGAILTCSLMNALVK 329
            ||..|.|:|||.:||:.|...:|.:|:|..||.::..:  ..||.:|::|||||.|.||:||
E. coli    68 SKVCTLALALEDVGPQAVQDKIGADPTGLPFNSVIALELHGGKPLSPLVNAGAIATTSLINA--- 129

  Fly   330 PDMTSAEIFDYTMSWFKRLS-----GGEYIGFNNAVFLSEREAADRN-------YALGFYMRENK 382
                    .:....|.:.|.     .||.:..::.|..||:.....|       |:.|:..
E. coli   130 --------ENVEQRWQRILHIQQQLAGEQVALSDEVNQSEQTTNFHNRAIAWLLYSAGYLY---- 182

  Fly   383 CFPKRTNLKEVMDFYFQCCSMETNCEAMSVIAASLANGGICPTTEEKVFRPEVIRDVLSIMHSCG 447
            |     :..|..|.|.:.||...|...::.:.|:||.||:.|.|.::|.:.:.:..:|:.|...|
E. coli   183 C-----DAMEACDVYTRQCSTLLNTIELATLGATLAAGGVNPLTHKRVLQADNVPYILAEMMMEG 242

  Fly   448 TYDYSGQFAFKVGLPAKSGVSGGMMLVIPNVMGIFAWSPPLDHLGNTVRGLQFCEELVSMFNFH 511
            .|..||.:|::||||.||||.||::.|:|.||||.|:|||||..||:|||.:....:.....::
E. coli   243 LYGRSGDWAYRVGLPGKSGVGGGILAVVPGVMGIAAFSPPLDEDGNSVRGQKMVASVAKQLGYN 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GLS	NP_001163129.1	EF-hand_14	110..201	CDD:465587
		Glutaminase	223..511	CDD:461499	106/301 (35%)
		Ank_2	540..622	CDD:463710
		ANK repeat	540..566	CDD:293786
		ANK repeat	568..600	CDD:293786
glsA	NP_415018.1	PRK12356	1..310	CDD:237073	108/324 (33%)