Protein Alignment GLS and glsl

DIOPT Version :9

• Sequence 1: NP_001163129.1
• Gene: GLS / 36396
• FlyBaseID: FBgn0261625
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: XP_001338211.4
• Gene: glsl / 797748
• ZFINID: ZDB-GENE-131127-106
• Length: 643
• Species: Danio rerio
• Alignment Length: 566
• Identity: 196/566 - (34%)
• Similarity: 310/566 - (54%)
• Gaps: 39/566 - (6%)

  Fly    84 SFYDTSSTPKTKEDNAKLHREQ---------------EQRNAEDVLFDMFASEETGLISMGKFLA 133
            ||.....|.:|..::.|||..|               :::.|.|||||.|||  .|.::..:|..
Zfish    96 SFISNGGTKRTVPEHEKLHAGQAWQHLGRQDTHQGHFKKKVAADVLFDSFAS--GGRVNCNQFFE 158

  Fly   134 GLKTTGIRRNDPRVRELMDNLKKVHKLNNYETGSSAETQHLNRETFKAVVAPNIVLIAKAFRQQF 198
            .|.::||.|.|||:::....::|:.:.:.          .::|..|...|...:..|.||.:.:|
Zfish   159 ALWSSGIIRTDPRIKDCYSLMRKLQEADG----------TVDRSMFHRCVTGFVSFILKALQGRF 213

  Fly   199 VIPDFTSFVKDIEDIYNRCKTNTLGKLADYIPQLARYNPDSWGLSICTIDGQRFSIGDVDVPFTL 263
            |||||::|.::.:.::.:||..:..|..:.:..    :...||:|:||:||||.|:||...|.||
Zfish   214 VIPDFSTFAEETQKLFIKCKQLSSVKEKEDVGD----SGTKWGISVCTVDGQRLSLGDWAEPCTL 274

  Fly   264 QSCSKPLTYAIALEKLGPKVVHSYVGQEPSGRNFNELVLDQNKKPHNPMINAGAILTCSLMNALV 328
            ...|.||.|.:|:::.|...||.|||.|...:..:...|.:...||:|::..|||:..||:....
Zfish   275 GEISWPLIYGLAVDQQGSDYVHRYVGMEEYSKYESLFTLTKQGVPHSPLVETGAIICTSLLQLAT 339

  Fly   329 KPDMTSAEIFDYTMSWFKRLSGGEYIGFNNAVFLSEREAADRNYALGFYMRENKCFPKRTNLKEV 393
            :|.....|.::..::..:||...|::..|...:...|:...|.:||.||::|.||||:...:...
Zfish   340 RPVTDEEEKYESVLNIIRRLCNKEHVNLNCTSYQDLRKDIVRLHALSFYLQEKKCFPEGVGINAT 404

  Fly   394 MDFYFQCCSMETNCEAMSVIAASLANGGICPTTEEKVFRPEVIRDVLSIMHSCGTYDYSGQFAFK 458
            :|...||.|.|..||:.:.:||:|||||:||.:.::|..|..:|..|::|...|..|||..|.|:
Zfish   405 LDLLLQCLSTEVTCESGAALAATLANGGLCPLSGDQVMSPHAVRSTLTMMQVAGMNDYSRAFHFR 469

  Fly   459 VGLPAKSGVSGGMMLVIPNVMGIFAWSPPLDHLGNTVRGLQFCEELVSMFNFHRYDNLKHLSNKK 523
            |.:||||..||.:::|:|.|:|:..|||.||..||:.|.:.|||||||.|..|.:|.........
Zfish   470 VSVPAKSSQSGVVLMVVPAVLGLMCWSPGLDCNGNSWRSVHFCEELVSTFQLHSFDIRTPFRQVL 534

  Fly   524 DPRKHRYETKGLSIVNLLFSAASGDVTALRRHRLSGMDITLADYDGRTALHLAASEGHLECVKFL 588
            ..|:.:.|::|..|:|:|.:|..||:.:|||:.|||.|:...|||||:|||:|||||.|:.::||
Zfish   535 CYRQWKVESEGYQIMNVLLAAYRGDLVSLRRYLLSGADVNAVDYDGRSALHVAASEGRLDVIRFL 599

  Fly   589 LE----QCHVPHNPKDRWGNLPVDEAENFGHCHVVEFLRSWAEKAD 630
            :|    .||:    |||||...:.||........::||:...:..:
Zfish   600 VENAGANCHL----KDRWGKTALQEAMRCNQDPAIQFLKKHTDNEE 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GLS	NP_001163129.1	Glutaminase	223..513	CDD:282773	109/289 (38%)
		Ank_4	538..589	CDD:290365	27/50 (54%)
		ANK	540..>622	CDD:238125	37/85 (44%)
		ANK repeat	540..566	CDD:293786	11/25 (44%)
		ANK repeat	568..600	CDD:293786	17/35 (49%)
		Ank_4	569..622	CDD:290365	23/56 (41%)
glsl	XP_001338211.4	Glutaminase	250..524	CDD:294588	108/273 (40%)
		Ank_5	536..587	CDD:290568	24/50 (48%)
		ANK	<553..633	CDD:238125	36/83 (43%)
		ANK repeat	579..611	CDD:293786	17/35 (49%)
		Ank_4	580..633	CDD:290365	23/56 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595540
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2066
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D175372at33208
OrthoFinder	1	1.000	-	-		FOG0001327
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12544
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X936
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.810