| Sequence 1: | NP_001163129.1 | Gene: | GLS / 36396 | FlyBaseID: | FBgn0261625 | Length: | 775 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055720.3 | Gene: | GLS / 2744 | HGNCID: | 4331 | Length: | 669 | Species: | Homo sapiens |
| Alignment Length: | 597 | Identity: | 296/597 - (49%) |
|---|---|---|---|
| Similarity: | 403/597 - (67%) | Gaps: | 54/597 - (9%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 30 ASAAEPVEDFDQETDLLKRAKFGHT-GKQLQQKIINEKNLRAPPLMNLVFANRKLSFYDTSSTPK 93
Fly 94 TKEDNAKLHREQEQRNAEDVLFDMFASEETGLISMGKFLAGLKTTGIRRNDPRVRELMDNLKKVH 158
Fly 159 KLNNYETGSSAETQHLNRETFKAVVAPNIVLIAKAFRQQFVIPDFTSFVKDIEDIYNRCKTNTLG 223
Fly 224 KLADYIPQLARYNPDSWGLSICTIDGQRFSIGDVDVPFTLQSCSKPLTYAIALEKLGPKVVHSYV 288
Fly 289 GQEPSGRNFNELVLDQNKKPHNPMINAGAILTCSLMNALVKPDMTSAEIFDYTMSWFKRLSGGEY 353
Fly 354 IGFNNAVFLSEREAADRNYALGFYMRENKCFPKRTNLKEVMDFYFQCCSMETNCEAMSVIAASLA 418
Fly 419 NGGICPTTEEKVFRPEVIRDVLSIMHSCGTYDYSGQFAFKVGLPAKSGVSGGMMLVIPNVMGIFA 483
Fly 484 WSPPLDHLGNTVRGLQFCEELVSMFNFHRYDNLKHLSNKKDPRKHRYETKGLSIVNLLFSAASGD 548
Fly 549 VTALRRHRLSGMDITLADYDGRTALHLAASEGHLECVKFLLEQCHVPHNPKDRWGNLPVDEAENF 613
Fly 614 GHCHVVEFLRSW 625 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| GLS | NP_001163129.1 | Glutaminase | 223..513 | CDD:282773 | 175/289 (61%) |
| Ank_4 | 538..589 | CDD:290365 | 33/50 (66%) | ||
| ANK | 540..>622 | CDD:238125 | 51/81 (63%) | ||
| ANK repeat | 540..566 | CDD:293786 | 15/25 (60%) | ||
| ANK repeat | 568..600 | CDD:293786 | 21/31 (68%) | ||
| Ank_4 | 569..622 | CDD:290365 | 33/52 (63%) | ||
| GLS | NP_055720.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 68..118 | 7/18 (39%) | |
| EF-hand_14 | 139..222 | CDD:407807 | 21/82 (26%) | ||
| Glutaminase | 244..528 | CDD:398563 | 160/283 (57%) | ||
| Highly mobile activation loop. /evidence=ECO:0000250|UniProtKB:D3Z7P3 | 315..322 | 5/6 (83%) | |||
| Ank_2 | 557..649 | CDD:403870 | 50/91 (55%) | ||
| ANK repeat | 557..583 | CDD:293786 | 14/25 (56%) | ||
| ANK repeat | 585..617 | CDD:293786 | 12/31 (39%) | ||
| ANK 1 | 585..614 | 11/28 (39%) | |||
| ANK 2 | 619..648 | 18/28 (64%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 647..669 | 13/21 (62%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165159380 | |
| Domainoid | 1 | 1.000 | 397 | 1.000 | Domainoid score | I749 |
| eggNOG | 1 | 0.900 | - | - | E1_COG2066 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H22726 | |
| Inparanoid | 1 | 1.050 | 592 | 1.000 | Inparanoid score | I984 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG52573 | |
| OrthoDB | 1 | 1.010 | - | - | D175372at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001327 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40899 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102294 | |
| Panther | 1 | 1.100 | - | - | O | PTHR12544 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2545 |
| SonicParanoid | 1 | 1.000 | - | - | X936 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.800 | |||||