DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nemy and cybrd1

DIOPT Version :9

Sequence 1:	NP_725208.1	Gene:	nemy / 36395	FlyBaseID:	FBgn0261673	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_001018336.1	Gene:	cybrd1 / 552960	ZFINID:	ZDB-GENE-050522-365	Length:	253	Species:	Danio rerio

Alignment Length:	223	Identity:	69/223 - (30%)
Similarity:	123/223 - (55%)	Gaps:	11/223 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 EYLLIVILSTILLVGVLVLTLFWVMFYRDGFAWSESPKQQFNLHPILMIAGFVTLSGFSILIYRL 121
            ::||..||::::.:..:.:.|.||:.||:|..| :....:||.||:||:.||:.|.|.:|::|||
Zfish     6 QFLLFFILASVVGIVSIAVALSWVLHYREGLGW-DGGAAEFNWHPLLMVIGFIFLQGIAIVVYRL 69

  Fly   122 ---CRCVKQIYVKLIHMFFHAVAIPCIALGFISVFASHDALHKVNFYSLHSWLGFVTMGMFVLQF 183
               .||.||: :||||...|.:|.....:..::||..|:|.:..|.||||||:|...:.::..|.
Zfish    70 PWTWRCSKQM-MKLIHAGLHILAFILAVISVVAVFVFHNAKNIPNMYSLHSWVGLAAVVLYPSQI 133

  Fly   184 VIGFFSFLVMLCCENKTYSCRSAMVPIHASLGLANFWLAIATSVTGLIEKERETVNEAGVSSENK 248
            |:|...:|:.:    .....|:|::|:|...||..|...||.::.|:.||...::...  :.::.
Zfish   134 VLGIAVYLIPV----TPVRVRAALMPLHIYSGLFIFISVIAAALMGITEKLIFSLKSP--AYKDS 192

  Fly   249 LVEHYITSAIGVTLIFIGIIVTFAVRRS 276
            ..|..:.:.:|:.:...|.:|.:...||
Zfish   193 PPEAVLVNVLGLLIAAFGALVVWIATRS 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nemy	NP_725208.1	Cytochrom_B561	99..233	CDD:281217	48/136 (35%)
cybrd1	NP_001018336.1	Cyt_b561_CYBRD1	34..186	CDD:176495	54/157 (34%)
		Heme b 1 binding. /evidence=ECO:0000250\|UniProtKB:Q53TN4	113..116		1/2 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	227..253
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1619
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1503869at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10106
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X568
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.880