Protein Alignment CG8646 and SGSH

DIOPT Version :9

• Sequence 1: NP_610807.3
• Gene: CG8646 / 36394
• FlyBaseID: FBgn0033763
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_000190.1
• Gene: SGSH / 6448
• HGNCID: 10818
• Length: 502
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 120/520 - (23%)
• Similarity: 190/520 - (36%)
• Gaps: 178/520 - (34%)

  Fly     8 CLLLPIIDAAEVEKSPAKP-NIIFILADDLGFNDVGFHGSAEIPTPNIDALAYSGIIL-NRYYVA 70
            |.||.::....     |:| |.:.:||||.||....::.|| |.||::||||...::. |.:...
Human     9 CALLLVLGLCR-----ARPRNALLLLADDGGFESGAYNNSA-IATPHLDALARRSLLFRNAFTSV 67

  Fly    71 PICTPSRSALMT-------GKYPIHTGMQHTVLYAAEPRGLPLEEKI--LPQYLNELGYTSHIAG 126
            ..|:|||::|:|       |.|.:|..:.|...:          :|:  ||..|::.|..:.|.|
Human    68 SSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSF----------DKVRSLPLLLSQAGVRTGIIG 122

  Fly   127 KWHLG-----HWKLKYTPLYRGFSSHVGFWSGHQDYNDHTAVENNQWGLDMRNGTQVAYDLHGHY 186
            |.|:|     .:...||. ..|....||                       ||.|::...:....
Human   123 KKHVGPETVYPFDFAYTE-ENGSVLQVG-----------------------RNITRIKLLVRKFL 163

  Fly   187 TTDVITDHSVKVIANHNATKGPLFLYVA----HAACHSSNPYNPL------------PVPD---- 231
            .|.               ...|.|||||    |...||...|...            .:||
Human   164 QTQ---------------DDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQ 213

  Fly   232 ----NDVIKMSHIPN--YKRRKFAAM---VSKMDNSVGQIVDQLRKSNMLENSIIIFSSDNGGPA 287
                .||:....:||  ..|...||.   |.:||..||.::.:||.:.:|.::::||:||||.|
Human   214 AYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIP- 277

  Fly   288 QGFNLNFASNYPLKGVKNTLWEGGVRAAGLMWSPLL-------KKSQRVSNQTMHIIDWLPTLLE 345
                      :| .|..|..|.|..       .|||       |:..:||...:.::|..||:|:
Human   278 ----------FP-SGRTNLYWPGTA-------EPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILD 324

  Fly   346 ---------AAGGQPAL----SNLSKQIDGQSIWRALVQDKASPRLNVLHNIDDIWGSAALSVGD 397
                     |..|...:    .:|...::.:.:|..:...::.      |.:...:...::....
Human   325 WFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSH------HEVTMSYPMRSVQHRH 383

  Fly   398 WKLVKGTNYR------------------------GSWDGWYGPAGERDPRLY----DWQLVGRSR 434
            ::||...|::                        |...|||     :|.|.|    .|:|..|||
Human   384 FRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWY-----KDLRHYYYRARWELYDRSR 443

  Fly   435  434
            Human   444  443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8646	NP_610807.3	AslA	25..459	CDD:225661	116/503 (23%)
		4-S	26..405	CDD:293753	103/443 (23%)
		DUF4976	<462..531	CDD:303608
SGSH	NP_000190.1	SGSH	24..472	CDD:293751	115/500 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810