Protein Alignment CG8646 and sgsh

DIOPT Version :10

• Sequence 1: NP_610807.3
• Gene: CG8646 / 36394
• FlyBaseID: FBgn0033763
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001116740.1
• Gene: sgsh / 563849
• ZFINID: ZDB-GENE-030131-4958
• Length: 511
• Species: Danio rerio
• Alignment Length: 567
• Identity: 133/567 - (23%)
• Similarity: 224/567 - (39%)
• Gaps: 161/567 - (28%)

  Fly     3 FLW-LICLLLPIIDAAEVEKSPAKPNIIFILADDLGFNDVGFHGSAEIPTPNIDALAYSGIIL-N 65
            |.| |:|||| ..|.......    |::.|:|||.|| :...:.:..:.||::.||:...:|. |
Zfish     5 FAWTLLCLLL-CFDVGGCRSR----NVLLIIADDGGF-ETDVYNNTVVQTPHLRALSKRSLIFKN 63

  Fly    66 RYYVAPICTPSRSALMT-------GKYPIHTGMQHTVLYAAEPRGLPLEEKILPQYLNELGYTSH 123
            .:.....|:||||.::|       |.|.:|.|:.|...:..        .:.||..|......:.
Zfish    64 AFTSVSSCSPSRSTILTGLPQHQNGMYGLHQGVHHFNSFDG--------VQSLPLLLKRANIHTG 120

  Fly   124 IAGKWHLGHWKLKYTPLYR-GFSSHVGFWSGHQDYNDHTAVENN--QWGLDMRNGTQVAYDLHGH 185
            |.||.|:|.     .|:|. .|:           |.:.|   |:  |.|   ||.|::...:...
Zfish   121 IIGKKHVGP-----GPVYPFDFA-----------YTEET---NSVLQVG---RNITKIKLLVRKF 163

  Fly   186 YTTDVITDHSVKVIANHNATKGPLFLYVA----HAACHSSNPYNPL------------PVPD--- 231
            :       .|.|...:....:.|.|||||    |...||...|...            .:||
Zfish   164 F-------QSHKEERSETKEERPFFLYVAFHDPHRCGHSQPQYGVFCEKFGNGESGMGRIPDWEP 221

  Fly   232 ----NDVIKMSH-IPN--YKRRKFAAM---VSKMDNSVGQIVDQLRKSNMLENSIIIFSSDNGGP 286
                .|.:|:.: ||:  ..|...||.   ||::|..:|.::::|||:....::::|:|||||
Zfish   222 KYYSPDQVKVPYFIPDTPAARADIAAQYTTVSRLDQGIGLVLEELRKAGFENDTLVIYSSDNG-- 284

  Fly   287 AQGFNLNFASNYPLKGVKNTLWEGGVRAAGLMWSPLLKKSQR---VSNQTMHIIDWLPTLLE--- 345
                       .|....:..|:..||:...|:.||  :..||   :|...:.::|..||:|:
Zfish   285 -----------IPFPNGRTNLYGSGVKEPMLLSSP--EHQQRWGKLSQAYVSLLDITPTILDWFS 336

  Fly   346 -------AAGGQPALSNLSKQIDGQSIWRALVQDKASPRL---NVLHNIDDIWGSAALSVGDWKL 400
                   .:..||.      ::.|:|:..||:.:.:...:   ..||.:...:...::..|.::|
Zfish   337 LPYPSYSLSMSQPV------ELTGRSLLPALISEPSWDTVFSSQSLHEVTMFYPMRSIHKGPYRL 395

  Fly   401 VKGTNYRGSW----DGWYGPAGERDPRLYDWQLVGRSRAGKALEALKMLPSRADQQRIRAAATVS 461
            :...:||..:    |.:..|..:        .|:.|:::|:.....|.|.....:||..
Zfish   396 LHNLHYRMPFPIDQDFYISPTFQ--------DLLNRTQSGRPTGWFKTLNEYYYRQRWE------ 446

  Fly   462 CPGQSSQGTSCVATAFSAPCLFHIRDDPCEQYNLA--KQYPEVVNAL 506
                                ||.:|.||.|:.|||  ..|.||:.:|
Zfish   447 --------------------LFDVRTDPMEKVNLAGDLDYSEVLESL 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8646	NP_610807.3	4-S	26..405	CDD:293753	101/434 (23%)
		DUF4976	<480..510	CDD:419068	13/29 (45%)
sgsh	NP_001116740.1	SGSH	25..481	CDD:293751	125/542 (23%)