Protein Alignment CG8646 and si:dkey-174i8.1

DIOPT Version :10

• Sequence 1: NP_610807.3
• Gene: CG8646 / 36394
• FlyBaseID: FBgn0033763
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_021336461.2
• Gene: si:dkey-174i8.1 / 563760
• ZFINID: ZDB-GENE-160114-17
• Length: 562
• Species: Danio rerio
• Alignment Length: 579
• Identity: 217/579 - (37%)
• Similarity: 303/579 - (52%)
• Gaps: 106/579 - (18%)

  Fly     8 CLLLPIIDAAE---VEKSPAKPNIIFILADDLGFNDVGFHGSAEIPTPNIDALAYSGIILNRYYV 69
            ||||.:|...|   |::....|:|:|::.||.|:||:|:||| ||.||.:|.||..|:.|..|||
Zfish     9 CLLLGLIHTIEGKVVKRGRVPPHIVFVMVDDQGYNDIGYHGS-EIQTPVLDQLAGEGVKLENYYV 72

  Fly    70 APICTPSRSALMTGKYPIHTGMQHTVLYAAEPRGLPLEEKILPQYLNELGYTSHIAGKWHLGHWK 134
            .|||:||||.||||:|.||||:||:::.|.:|..||.:...||:.|.|.||::|:.||||||..:
Zfish    73 QPICSPSRSQLMTGRYQIHTGLQHSIIRARQPLCLPPDTPTLPERLQEAGYSTHMVGKWHLGFCR 137

  Fly   135 LKYTPLYRGFSSHVGFWSGHQDYNDHTAVENNQ-WGLDMRNGTQVAYDLHGHYTTDVITDHSVKV 198
            .:..|..|||.|.:|..:|..|:....:.:..: .|.|:.:|.:.|::|.|:|:|.:.|:....:
Zfish   138 PECLPTSRGFQSFLGSLTGSGDHFSFQSCDGTEACGFDLHDGDRPAWELRGNYSTRLYTERVKDI 202

  Fly   199 IANHNATKGPLFLYVAHAACHSSNPYNPLPVPDNDVIKMSHIPNYKRRKFAAMVSKMDNSVGQIV 263
            :..|:..| |||||||..|.|:     ||..|.:.:.:...:.|..||.:|||||.:|.|||:||
Zfish   203 LRRHDHRK-PLFLYVALQAVHT-----PLQAPGHLLRRYQALGNRPRRHYAAMVSGVDESVGEIV 261

  Fly   264 DQLRKSNMLENSIIIFSSDNGG-PAQGFNLNFASNYPLKGVKNTLWEGGVRAAGLMWSPLLKKSQ 327
            .:||:....:||::|:|||||| |..|     ..|:||:|.|.:.|||||||.|.:.|||||:..
Zfish   262 SELRERGYYDNSVLIYSSDNGGQPLSG-----GCNWPLRGGKGSYWEGGVRAVGFVHSPLLKRKG 321

  Fly   328 RVSNQTMHIIDWLPTLLEAAGGQPALSNLSKQIDGQSIWRALVQDKASPRLNVLHNID------- 385
            .||:..:||.||.||||..||.:.:.||   .:|||.:|..:..|...||..:|.|||
Zfish   322 VVSHALIHISDWYPTLLSLAGYRESDSN---HLDGQDVWETISSDLPCPRTEILFNIDPVSRRHG 383

  Fly   386 ------------DIWGS---AALSVGDWKLVKGTNYRGSW----------DGWYGPAGERDPRLY 425
                        .||.:   ||:..|||||:.|....|.|          ..|.|....||.|
Zfish   384 DINPKLLTLNGFGIWDTGVRAAIRAGDWKLLTGNIGDGDWFPPQTMPGGPQQWQGMEKRRDQR-- 446

  Fly   426 DWQLVGRSRAGKALEALKMLPSRADQQRIRAAATVSCPGQSSQGTSCVATAFSAPCLFHIRDDPC 490
                      ||::                                         .||:|..||.
Zfish   447 ----------GKSV-----------------------------------------WLFNITADPY 460

  Fly   491 EQYNLAKQYPEVVNALMTELERFNATAVPPSNKPADPRADPRFWNYTWTNF-GDYQNND 548
            |:.:||:..||||..|:|.|..:|.|||.|.|.|.||.|||:.....||.: |..::.|
Zfish   461 ERADLAEARPEVVKVLLTRLSEYNRTAVSPRNPPDDPMADPQLHGGVWTPWLGQEEHRD 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8646	NP_610807.3	4-S	26..405	CDD:293753	170/402 (42%)
		DUF4976	<480..510	CDD:419068	14/29 (48%)
si:dkey-174i8.1	XP_021336461.2	None