Protein Alignment CG8646 and ARSF

DIOPT Version :10

• Sequence 1: NP_610807.3
• Gene: CG8646 / 36394
• FlyBaseID: FBgn0033763
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_011543824.1
• Gene: ARSF / 416
• HGNCID: 721
• Length: 607
• Species: Homo sapiens
• Alignment Length: 620
• Identity: 147/620 - (23%)
• Similarity: 232/620 - (37%)
• Gaps: 184/620 - (29%)

  Fly     3 FLWLICLLLPIIDAAEVEKSPAKPNIIFILADDLGFNDVGFHGSAEIPTPNIDALAYSGIILNRY 67
            |:.|:|.||....|..|...  ||||:.|:.||||..|:|.:|:..:.||:||.||..|:.|.::
Human    26 FMSLVCALLNTCQAHRVHDD--KPNIVLIMVDDLGIGDLGCYGNDTMRTPHIDRLAREGVRLTQH 88

  Fly    68 Y-VAPICTPSRSALMTGKYPIHTGM-----QHTVLYAAEPRGLPLEEKILPQYLNELGYTSHIAG 126
            . .|.:|:|||||.:||:|||.:||     :..:...|.|.||||.|..|...|.:.||::.:.|
Human    89 ISAASLCSPSRSAFLTGRYPIRSGMVSSGNRRVIQNLAVPAGLPLNETTLAALLKKQGYSTGLIG 153

  Fly   127 KWHLG----------HWKLKYTPLYRGFSSHVGF--------WSGHQDYNDHTAVENNQW----- 168
            |||.|          |....|     ||..:.|.        |. ....|...|.|:..|
Human   154 KWHQGLNCDSRSDQCHHPYNY-----GFDYYYGMPFTLVDSCWP-DPSRNTELAFESQLWLCVQL 212

  Fly   169 ----GLDMRNG--------------------------------TQVAYD---LHGHYTTD----- 189
                .|.:..|                                :.:.:|   :.||..|:
Human   213 VAIAILTLTFGKLSGWVSVPWLLIFSMILFIFLLGYAWFSSHTSPLYWDCLLMRGHEITEQPMKA 277

  Fly   190 -----VITDHSVKVIANHNATKGPLFLYVAHAACHSSNPYNPLPVPDNDVIKMSHIPNYKRRKFA 249
                 ::...::..:..|:.....||....|.       :.|||..| |....|     |...:.
Human   278 ERAGSIMVKEAISFLERHSKETFLLFFSFLHV-------HTPLPTTD-DFTGTS-----KHGLYG 329

  Fly   250 AMVSKMDNSVGQIVDQLRKSNMLENSIIIFSSDNGGPAQ---------GFNLNFASNYPLKGVKN 305
            ..|.:||:.||:|:|.:....:..|:::.|:||:||..:         |:|..:.....:.|
Human   330 DNVEEMDSMVGKILDAIDDFGLRNNTLVYFTSDHGGHLEARRGHAQLGGWNGIYKGGKGMGG--- 391

  Fly   306 TLWEGGVRAAGLMWSPLLKKSQRVSNQTMHIIDWLPTLLEAAGGQ-PALSNLSKQIDGQSIWRAL 369
              ||||:|..|::..|....:.|:..:...::|.|||:...:||. |.    .:.|||:.: ..|
Human   392 --WEGGIRVPGIVRWPGKVPAGRLIKEPTSLMDILPTVASVSGGSLPQ----DRVIDGRDL-MPL 449

  Fly   370 VQDKASPRLNVLHNIDDIWGSAALSVGDWKLVKGTNYRGSWDGWYGPAGERDPRLYDWQLVGRSR 434
            :|.      ||.|:..:..               .:|.||:
Human   450 LQG------NVRHSEHEFL---------------FHYCGSY------------------------ 469

  Fly   435 AGKALEALKMLPSRADQQRIRAAATVSCPGQSSQGTSCVATAF-----------SAPCLFHIRDD 488
                |.|::.:| :.|...:..|..|:...|......|..|:.           :.|.||.:..|
Human   470 ----LHAVRWIP-KDDSGSVWKAHYVTPVFQPPASGGCYVTSLCRCFGEQVTYHNPPLLFDLSRD 529

  Fly   489 PCEQYNLAKQ----YPEVVNALMTELERFNATAVP 519
            |.|...|...    :..|:..:...|:....|.||
Human   530 PSESTPLTPATEPLHDFVIKKVANALKEHQETIVP 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8646	NP_610807.3	4-S	26..405	CDD:293753	115/466 (25%)
		DUF4976	<480..510	CDD:419068	8/33 (24%)
ARSF	XP_011543824.1	ALP_like	46..570	CDD:474031	140/598 (23%)