Protein Alignment CG8646 and ARSL

DIOPT Version :9

• Sequence 1: NP_610807.3
• Gene: CG8646 / 36394
• FlyBaseID: FBgn0033763
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001269557.1
• Gene: ARSL / 415
• HGNCID: 719
• Length: 614
• Species: Homo sapiens
• Alignment Length: 460
• Identity: 116/460 - (25%)
• Similarity: 181/460 - (39%)
• Gaps: 132/460 - (28%)

  Fly     2 WFLWLICLLLPIIDAAEVEKSPAKPNIIFILADDLGFNDVGFHGSAEIPTPNIDALAYSGIILNR 66
            |...::.:||.:..:|..:.|.::|||:.::|||||..|:|.:|:..:.|||||.||..|:.|.:
Human    39 WLPAMLAVLLSLAPSASSDISASRPNILLLMADDLGIGDIGCYGNNTMRTPNIDRLAEDGVKLTQ 103

  Fly    67 YY-VAPICTPSRSALMTGKYPIHTGMQHTVLY-----AAEPRGLPLEEKILPQYLNELGYTSHIA 125
            :. .|.:|||||:|.:||:||:.:||..::.|     .....|||..|....:.|.|.||.:.:.
Human   104 HISAASLCTPSRAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYATGLI 168

  Fly   126 GKWHLG--------HWKLKYTPLYRGFSSHVG--------------------------------- 149
            ||||||        |.   :.||:.||....|
Human   169 GKWHLGLNCESASDHC---HHPLHHGFDHFYGMPFSLMGDCARWELSEKRVNLEQKLNFLFQVLA 230

  Fly   150 ----------------------FWSG------------------HQDYNDHTAVENNQWGLDMRN 174
                                  .||.                  |.|.            ..|||
Human   231 LVALTLVAGKLTHLIPVSWMPVIWSALSAVLLLASSYFVGALIVHADC------------FLMRN 283

  Fly   175 GTQVAYDLHGHYTTDVITDHSVKVIANHNATKGPLFLYVAHAACHSSNPYNPLPVPDNDVIKMSH 239
            .|.....:....||.:|.......:..:.  .||..|:|:....|.     ||...:|.:.|..|
Human   284 HTITEQPMCFQRTTPLILQEVASFLKRNK--HGPFLLFVSFLHVHI-----PLITMENFLGKSLH 341

  Fly   240 IPNYKRRKFAAMVSKMDNSVGQIVDQLRKSNMLENSIIIFSSDNGGPAQ---------GFNLNFA 295
                  ..:...|.:||..||:|:|.|....:..:::|.|:||:||..:         |:|..:.
Human   342 ------GLYGDNVEEMDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYK 400

  Fly   296 SNYPLKGVKNTLWEGGVRAAGLMWSPLLKKSQRVSNQTMHIIDWLPTLLEAAGGQPALSNLSKQI 360
            ....:.|     ||||:|..|:...|.:..:.||..:...::|..||::..|||:.....:   |
Human   401 GGKGMGG-----WEGGIRVPGIFRWPGVLPAGRVIGEPTSLMDVFPTVVRLAGGEVPQDRV---I 457

  Fly   361 DGQSI 365
            |||.:
Human   458 DGQDL 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8646	NP_610807.3	AslA	25..459	CDD:225661	111/437 (25%)
		4-S	26..405	CDD:293753	111/436 (25%)
		DUF4976	<462..531	CDD:303608
ARSL	NP_001269557.1	ALP_like	62..585	CDD:355016	111/437 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810