Protein Alignment CG8646 and STS

DIOPT Version :10

• Sequence 1: NP_610807.3
• Gene: CG8646 / 36394
• FlyBaseID: FBgn0033763
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001307679.1
• Gene: STS / 412
• HGNCID: 11425
• Length: 590
• Species: Homo sapiens
• Alignment Length: 620
• Identity: 150/620 - (24%)
• Similarity: 241/620 - (38%)
• Gaps: 158/620 - (25%)

  Fly     1 MWFLWLICLLLPIIDAAEVEKSPA-KPNIIFILADDLGFNDVGFHGSAEIPTPNIDALAYSGIIL 64
            ::|||            |.|...| :||||.::|||||..|.|.:|:..|.|||||.||..|:.|
Human    20 LFFLW------------EAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKL 72

  Fly    65 NRYYVA-PICTPSRSALMTGKYPIHTGMQH-----TVLYAAEPRGLPLEEKILPQYLNELGYTSH 123
            .::..| |:|||||:|.|||:||:.:||..     ..|:.|...|||.:|....:.|.:.||::.
Human    73 TQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTA 137

  Fly   124 IAGKWHLG---HWKLKYT--PLYRGFSSHVGFWSGHQDYNDHTAVENNQWGLDMRNGTQVAYDLH 183
            :.||||||   |.|..:.  ||:.||:...|.  ...:..|....|.:.:....:....:...:.
Human   138 LIGKWHLGMSCHSKTDFCHHPLHHGFNYFYGI--SLTNLRDCKPGEGSVFTTGFKRLVFLPLQIV 200

  Fly   184 GHYTTDVITDHSVKVIANHNATKGPLFLYVAHAA---------CHSSNPYNPLPVPDNDVIK--M 237
            |   ..::|..::..:...:...|..|..:..||         .|...|.|...:.:.::|:  |
Human   201 G---VTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPLNCFMMRNYEIIQQPM 262

  Fly   238 S---------------------------------HIPNYKRRKFAA---------MVSKMDNSVG 260
            |                                 |...:..:.||.         .|.:||.|||
Human   263 SYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQHGVYGDAVEEMDWSVG 327

  Fly   261 QIVDQLRKSNMLENSIIIFSSDNGGPAQGFN----LNFASNYPLKGVKNTLWEGGVRAAGLM-WS 320
            ||::.|.:..:..:::|.|:||.|...:..:    ::..||...||.|...||||:|..|:: |.
Human   328 QILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGKANNWEGGIRVPGILRWP 392

  Fly   321 PLLKKSQRVSNQTMHIIDWLPTLLEAAGGQPALSNLSKQIDGQSIWRALVQDKASPRLNVLHNID 385
            .:::..|::...|.: :|..||:.:.||.......:   |||:.: ..|::.| |.|.:  |...
Human   393 RVIQAGQKIDEPTSN-MDIFPTVAKLAGAPLPEDRI---IDGRDL-MPLLEGK-SQRSD--HEFL 449

  Fly   386 DIWGSAALSVGDWKLVKGTNYRGSWDGW-----YGPAGERDPRLYDWQLVGRSRAGKALEALKML 445
            ..:.:|.|:...|.....|:.   |..:     :.|.|...
Human   450 FHYCNAYLNAVRWHPQNSTSI---WKAFFFTPNFNPVGSNG------------------------ 487

  Fly   446 PSRADQQRIRAAATVSCPGQSSQGTSCVATAFSAPCLFHIRDDPCEQYNLA----KQYPEVVNAL 506
                    ..|.....|.|.       ..|....|.||.|..||.|:..|.    .::.|::..:
Human   488 --------CFATHVCFCFGS-------YVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVM 537

  Fly   507 MTELERFNATAVPPSNKPADPRADPRFWNYTWTNF 541
            ....:|...|.         |....:|   :|.||
Human   538 QEAADRHTQTL---------PEVPDQF---SWNNF 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8646	NP_610807.3	4-S	26..405	CDD:293753	120/447 (27%)
		DUF4976	<480..510	CDD:419068	9/33 (27%)
STS	NP_001307679.1	ES	33..557	CDD:293778	141/590 (24%)