DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8646 and gnsb

DIOPT Version :9

Sequence 1:	NP_610807.3	Gene:	CG8646 / 36394	FlyBaseID:	FBgn0033763	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_956135.2	Gene:	gnsb / 327635	ZFINID:	ZDB-GENE-030131-5846	Length:	507	Species:	Danio rerio

Alignment Length:	418	Identity:	100/418 - (23%)
Similarity:	169/418 - (40%)	Gaps:	111/418 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWFLWLICLLLPIIDAAEVEKSPAKPNIIFILADDLGFNDVGFHGSAEIPTPNIDALAYSGIIL- 64
            ::|.:..|..            .:|.|||.||.||   .|....|...:.... :.:..:|...
Zfish    20 LFFFFFTCAF------------SSKNNIILILTDD---QDEQMGGMTPMKKTR-ELIGDAGATFS 68

  Fly    65 NRYYVAPICTPSRSALMTGKYPIHTGMQHTVLY-----------AAEPRGLPLEEKILPQYLNEL 118
            |.:...|:|.||||:.::|:|| |..:.|....           .|||...|:       |||::
Zfish    69 NAFTSTPLCCPSRSSFLSGRYP-HNHLVHNNSVEGNCSSAAWQKTAEPFAFPV-------YLNKM 125

  Fly   119 GYTSHIAGKWHLGHWKLKYTPLYRGFSSHV--GF--WS---GHQDYNDHTAVENNQWGLDMRNGT 176
            .|.:...|| :|..:..|..    |..:||  |:  |.   |:..|.::|...|   |.:.::|.
Zfish   126 RYQTFYCGK-YLNQYGSKDA----GGVAHVPPGWDQWHALVGNSKYYNYTLSVN---GKEEKHGD 182

  Fly   177 QVAYDLHGHYTTDVITDHSVKVIANHNATKGPLFLYVAHAACHS--------------------- 220
            ....|    |.||::.:.|:..:...:.:. |.|:.:...|.||
Zfish   183 SYEKD----YLTDLVLNRSLHFLEERSPSH-PFFMMLCPPAPHSPWTAAPQYSGSFSGVKAPRNG 242

  Fly   221 -------------SNPYNPLPVPDNDVIKMSHIPNYKRRKFAAMVSKMDNSVGQIVDQLRKSNML 272
                         ..|.||:|....|     ::.|..||::..::| :|:.|.:::.:|.....|
Zfish   243 SFNKPGTDKHWLLRQPANPMPNSSID-----YLDNAFRRRWQTLLS-VDDLVERLLKKLDSVKEL 301

  Fly   273 ENSIIIFSSDNGGPAQGFNLNFASNYPLKGVKNTLWEGGVRAAGLMWSPLLKKSQRVSNQTMHII 337
            :|:.|.::||:|.....|:|      |:.  |..|:|..:|...|:..|.:|..|.:.:..:: |
Zfish   302 DNTYIFYTSDHGYHTGQFSL------PID--KRQLYEFDIRIPLLVRGPGIKAKQTLQSPVLN-I 357

  Fly   338 DWLPTLLEAAGGQPALSNLSK-QIDGQS 364
            |...|:|:.||     .|||. .:||||
Zfish   358 DLPMTILDIAG-----VNLSTVNMDGQS 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8646	NP_610807.3	AslA	25..459	CDD:225661	98/394 (25%)
		4-S	26..405	CDD:293753	97/393 (25%)
		DUF4976	<462..531	CDD:303608
gnsb	NP_956135.2	AslA	34..496	CDD:225661	97/392 (25%)
gnsb	NP_956135.2	G6S	34..480	CDD:293766	97/392 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910