Protein Alignment CG8646 and ARSK

DIOPT Version :10

• Sequence 1: NP_610807.3
• Gene: CG8646 / 36394
• FlyBaseID: FBgn0033763
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_937793.1
• Gene: ARSK / 153642
• HGNCID: 25239
• Length: 536
• Species: Homo sapiens
• Alignment Length: 578
• Identity: 127/578 - (21%)
• Similarity: 203/578 - (35%)
• Gaps: 179/578 - (30%)

  Fly     1 MWFLWL-------ICLLLPIIDAAEVEKSPAK-PNIIFILADDLGFNDVGFH-GSAEIPTPNIDA 56
            |..||:       :.:|.|  .|.|..:..|| ||::.:::|... ..:.|| ||..:..|.|:.
Human     1 MLLLWVSVVAALALAVLAP--GAGEQRRRAAKAPNVVLVVSDSFD-GRLTFHPGSQVVKLPFINF 62

  Fly    57 LAYSGI-ILNRYYVAPICTPSRSALMTGKYPIHTGMQHTVLYAAEPRGLPLEEKILPQY------ 114
            :...|. .||.|..:|||.|||:|:.:|.:...|...:..      :||.      |.|
Human    63 MKTRGTSFLNAYTNSPICCPSRAAMWSGLFTHLTESWNNF------KGLD------PNYTTWMDV 115

  Fly   115 LNELGYTSHIAGKWHLGHWKLKYTPLYRGFSSHVGFWSGHQDYNDHTAVENNQWGLDM----RNG 175
            :...||.:...|       ||.||..:...|:.|..|:  :|    .|....|.|..|    ||.
Human   116 MERHGYRTQKFG-------KLDYTSGHHSISNRVEAWT--RD----VAFLLRQEGRPMVNLIRNR 167

  Fly   176 TQVAYDLHGHYTTDVITDHSVKVIANHNATKGPLFLYVAHAACHSSNPYNPLPVPDND------- 233
            |:|.........||...:...|...|:..   |..:|:      ..|..:|.|.|.:.
Human   168 TKVRVMERDWQNTDKAVNWLRKEAINYTE---PFVIYL------GLNLPHPYPSPSSGENFGSST 223

  Fly   234 -------VIKMSH----IPNYK------------------------------RRKFAAMVSKMDN 257
                   :.|:||    ||.:.                              |..:.||.::.|.
Human   224 FHTSLYWLEKVSHDAIKIPKWSPLSEMHPVDYYSSYTKNCTGRFTKKEIKNIRAFYYAMCAETDA 288

  Fly   258 SVGQIVDQLRKSNMLENSIIIFSSDNGGPAQGFNLNFASNYPLKGVKNTLWEGGVRAAGLMWSPL 322
            .:|:|:..|.:.::|:.:|:|:|||:|..|......:         |.:::|.......||..|.
Human   289 MLGEIILALHQLDLLQKTIVIYSSDHGELAMEHRQFY---------KMSMYEASAHVPLLMMGPG 344

  Fly   323 LKKSQRVSNQTMHIIDWLPTLLEAAGGQPALSNLSKQIDGQSIWRALVQDKASPRLNVLHNIDDI 387
            :|...:||| .:.::|..||:|:.| |.|...|||    |.|:     ...:|......|.:.::
Human   345 IKAGLQVSN-VVSLVDIYPTMLDIA-GIPLPQNLS----GYSL-----LPLSSETFKNEHKVKNL 398

  Fly   388 WGSAALSVGDWKLVKGTNYRGSWDGWYGPAGERDPRLYDWQLVGRSRAGKALEALKMLPSRADQQ 452
            .....||......|..:.|.              .|...|:.:..|.....|
Human   399 HPPWILSEFHGCNVNASTYM--------------LRTNHWKYIAYSDGASIL------------- 436

  Fly   453 RIRAAATVSCPGQSSQGTSCVATAFSAPCLFHIRDDPCEQYNLAKQYPEVVNALMTEL 510
                                       |.||.:..||.|..|:|.::||:..:|..:|
Human   437 ---------------------------PQLFDLSSDPDELTNVAVKFPEITYSLDQKL 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8646	NP_610807.3	4-S	26..405	CDD:293753	101/438 (23%)
		DUF4976	<480..510	CDD:419068	11/29 (38%)
ARSK	NP_937793.1	ARSK	32..447	CDD:293781	110/523 (21%)