Protein Alignment CG8646 and LOC1270591

DIOPT Version :10

• Sequence 1: NP_610807.3
• Gene: CG8646 / 36394
• FlyBaseID: FBgn0033763
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_564139.4
• Gene: LOC1270591 / 1270591
• VectorBaseID: AGAMI1_014448
• Length: 662
• Species: Anopheles gambiae
• Alignment Length: 548
• Identity: 236/548 - (43%)
• Similarity: 328/548 - (59%)
• Gaps: 26/548 - (4%)

  Fly     6 LICLLL-----PIIDAAEVEKSPAKPNIIFILADDLGFNDVGFHGSAEIPTPNIDALAYSGIILN 65
            |:|:::     .:..||..:..|.:|:|:.|.|||:|:||||||||.:|.||:||||||.|:|||
Mosquito     9 LVCIIVAAGYRTLAVAAYGQNPPKRPHIVLITADDMGWNDVGFHGSNQIATPHIDALAYDGVILN 73

  Fly    66 RYYVAPICTPSRSALMTGKYPIHTGMQHTVLYAAEPRGLPLEEKILPQYLNELGYTSHIAGKWHL 130
            |:|.||:|||||:|||||::||:.||||.|:.:.||.||.|:::|:|||....||.:|:.|||||
Mosquito    74 RHYSAPMCTPSRAALMTGRHPINVGMQHYVIDSDEPWGLGLDQRIMPQYFRAAGYRTHMIGKWHL 138

  Fly   131 GHWKLKYTPLYRGFSSHVGFWSGHQDYNDHTAVENNQW--GLDMRNGTQVAYDLHGHYTTDVITD 193
            |.:...|.|..|||.:|:|:...:.||..:.:..|:..  |.|||....|.|..:|.|.||..|.
Mosquito   139 GFFTEHYIPTNRGFDTHIGYLGPYVDYWSYVSKMNSGTFEGYDMRQNQFVNYAANGTYATDYFTS 203

  Fly   194 HSVKVIANHNATKGPLFLYVAHAACHSSNPYNPLPVPDNDVIKMSHIPNYKRRKFAAMVSKMDNS 258
            .:..:||.|..:..|:.|.:.|.|.|:.|..:||..|...:.:.::|.|..||.:|||:||:|:|
Mosquito   204 AARDIIAQHGKSGQPMLLVMNHLAPHAGNDDDPLQAPQETIDRFAYIGNKDRRTYAAMMSKLDDS 268

  Fly   259 VGQIVDQLRKSNMLENSIIIFSSDNGGPAQGFNLNFASNYPLKGVKNTLWEGGVRAAGLMWSPLL 323
            ||.:.:.||.:.||:||||:|.|||||..:|.:.|..||||.:|.|::.|||.||.|.|:|||||
Mosquito   269 VGAVYESLRANGMLDNSIIVFLSDNGGVTRGMHSNTGSNYPFRGQKHSPWEGAVRTAALIWSPLL 333

  Fly   324 KKSQRVSNQTMHIIDWLPTLLEAAGGQPALSNLS-KQIDGQSIWRALVQDKASPRLNVLHNIDDI 387
            |.:||||||..||.||||||..|||  .||.|.| ..|||...|.||.....:||..:::|:|:|
Mosquito   334 KDTQRVSNQWFHISDWLPTLASAAG--IALGNSSFSDIDGIDQWEALAYGTGNPRQRLMNNLDEI 396

  Fly   388 WGSAALSVGDWKLVKGTNYRGSWDGWYGPAGERDPRLYDWQLVGRSRAGKALEALKMLPSRADQQ 452
            :|..:.....:|.:.||...|..|.|||.....|....|.|.:....|.:...|     .|.|::
Mosquito   397 FGYTSYMENGFKYINGTTLNGVNDAWYGETDPLDQLPDDEQYLSSVMATRIARA-----GRLDEK 456

  Fly   453 RI---RAAATVSCPGQSSQGTSCVATAFSAPCLFHIRDDPCEQYNLAKQYPEVVNALMTELERFN 514
            .|   |..|||:| |.|.....|  .....||||.|.:||||.::::.:||:.:..:...||.:.
Mosquito   457 LISYLRRHATVNC-GNSIATKPC--NPLVKPCLFDIINDPCEMHDISDEYPKRLRGIRNRLELYR 518

  Fly   515 ATAVPPSNKPADPRADP-RF---WNYTW 538
            ..|..|.|:|.||.||| :|   ||: |
Mosquito   519 LRAAKPRNRPHDPEADPSKFGGVWNW-W 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8646	NP_610807.3	4-S	26..405	CDD:293753	183/381 (48%)
		DUF4976	<480..510	CDD:419068	11/29 (38%)
LOC1270591	XP_564139.4	None