Protein Alignment ZnT49B and MMT1

DIOPT Version :9

• Sequence 1: NP_725207.1
• Gene: ZnT49B / 36393
• FlyBaseID: FBgn0033762
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_013902.1
• Gene: MMT1 / 855215
• SGDID: S000004789
• Length: 510
• Species: Saccharomyces cerevisiae
• Alignment Length: 514
• Identity: 100/514 - (19%)
• Similarity: 185/514 - (35%)
• Gaps: 167/514 - (32%)

  Fly   239 KIKRRSPYEQEPPMTVYWRRDVEAKAVEVWGSKENLLRERLKREVE-----------RKQYQQI- 291
            |:::.|...|:.|..|         .||:         ..|||:.|           ..|||::
Yeast    36 KVEKSSIINQKDPNKV---------RVEI---------NELKRQAEIEKAAIKELEKNPQYQKLA 82

  Fly   292 --YDSADLFTVKR------------RLRDYRR------------EMGSRTK-------------- 316
              ::|.|...::.            .:|||:.            .:.|.|.
Yeast    83 EAFNSHDHVHLRESETEQNDIISLGTIRDYKSSKCEQADKPSSLNLHSHTHSHGHTHSHAAHNPL 147

  Fly   317 VMLDNRKESEKSG-QVVATAIAINAANLLFKAGGWLYSGSHSMFAEVIHSLADLINQLILAFGIY 380
            ::|...:..:.:| ::....:.:|....:.|..|.:...|.::||:.||:::|:::.|:....:.
Yeast   148 LVLSTEQIRKNAGVRITWVGLGVNVGIAIGKFFGGIVFHSQALFADAIHAISDMVSDLLTLLSVG 212

  Fly   381 KSSQSPDIDHPYGYMNMRYVSSLISGVGIFCVGCGLSIYHGIDGILHPEPITDLFWVYCILMGSL 445
            .::..|..|:||||..:..|.||  .|.......|:||  |...:             |.|:|.:
Yeast   213 LAANKPTADYPYGYGKIETVGSL--AVSTILAMAGISI--GWSSL-------------CALVGPV 260

  Fly   446 VSEGATLVVAINELKRSAKENNMSFKDYVISGKDPCVNVVLCEDAAAVTGVMVAAACMGLSSYTG 510
            :..  |::..|..|..:     .::.:.:|            ||...:....:|||.:....:
Yeast   261 IPH--TIIDTIGNLGHA-----HTYSEDII------------EDVTDINAAWIAAASIAAKEW-- 304

  Fly   511 SPIFDAAGSLVIGALLGAVASFIIYTNAN------------------ALVGIS----IASERLEK 553
              ||.|...:.|.            ||:|                  |||.||    :..:.|:.
Yeast   305 --IFRATRKIAIN------------TNSNVLMANAWHHRVDSLTSLVALVAISTGYLVNIQSLDT 355

  Fly   554 INSALEADVMIRAIYDVKGIDIGNARVRYKAELDFDGRELTRSYLDKQDLAKLLTTVRGFQKVED 618
            |...:.:.::|:|  ..:|:.|....:..::....|.|.|....|.|..|.||::. ...||...
Yeast   356 IGGLIVSGLIIKA--GGEGMCIAIKELIDQSVSRDDPRYLEIETLVKDTLNKLISN-NNSQKPYG 417

  Fly   619 L-ESFLLDQGENI-------------VDLMG-GEIDRIEMNLR----TQFPEIRHVDLE 658
            | |..||..|.|:             .:::| .|.:.:..:||    .:...:|.:|:|
Yeast   418 LKELTLLSSGPNLRGHLTLEVPLQKWGNILGVNEFEIVTHHLRNVLTNEVSNLRRLDIE 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT49B	NP_725207.1	Cation_efflux	343..542	CDD:279834	43/216 (20%)
MMT1	NP_013902.1	FieF	150..488	CDD:223131	79/382 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0053
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3187
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2191
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.880