Protein Alignment ZnT49B and Slc30a9

DIOPT Version :10

• Sequence 1: NP_725207.1
• Gene: ZnT49B / 36393
• FlyBaseID: FBgn0033762
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_848766.2
• Gene: Slc30a9 / 109108
• MGIID: 1923690
• Length: 567
• Species: Mus musculus
• Alignment Length: 579
• Identity: 261/579 - (45%)
• Similarity: 355/579 - (61%)
• Gaps: 59/579 - (10%)

  Fly   127 PVLAASAINLRSTSTGVAT----GAVGLGESSG--SVMNPPETVKSAPKNSPSGAVL-------- 177
            |.|||:|...|.:...:..    .|...|.|.|  :||.........|...|..:::
Mouse     3 PGLAAAAAAHRCSWAALCRLGGGRAATRGRSQGWKNVMTFESFTYVVPDIHPHLSIINQVKLYST 67

  Fly   178 -AEKAGEGIRTSPPAEVTPPAP----------VIPLKRPRFDYRAS------------LERNFVT 219
             .:|.|:|.:| |.|:..|...          ..|||:.....|..            .:.||:|
Mouse    68 NVQKGGQGSQT-PKADKVPSLTQTVENIGAELKAPLKQDPLQVRVKAVLKKRDYGSKYTKNNFIT 131

  Fly   220 PNRAISDFLLTAAQLESLPKIKRRSPYEQEPPMTVYWRRDVEAKAVEVWGSKENLLRERLKREVE 284
            ..|||::|.|.::.||.|.||:||||::.....||:.|.||||||:|||||.|.|.||:..|:..
Mouse   132 GVRAINEFCLKSSDLEQLRKIRRRSPHDDTESFTVFLRSDVEAKALEVWGSLEALAREKKLRKEA 196

  Fly   285 RKQYQQIYDSADLFTVKRRLRDYRREMGSRTKVMLDNRKESEKS--------GQVVATAIAINAA 341
            ..:|::     .||..:|.||:|...:|        |.|...::        |:||..||.||..
Mouse   197 EIEYRE-----RLFRNQRILREYGDFLG--------NTKPRSRAVSVFLKGPGKVVMVAICINGL 248

  Fly   342 NLLFKAGGWLYSGSHSMFAEVIHSLADLINQLILAFGIYKSSQSPDIDHPYGYMNMRYVSSLISG 406
            |..||...|:|:||.|||:|.||||:|..||.:||.||.||.|:||..||||:.||||:||||||
Mouse   249 NCFFKFLAWIYTGSASMFSEAIHSLSDTCNQGLLALGISKSVQTPDPSHPYGFSNMRYISSLISG 313

  Fly   407 VGIFCVGCGLSIYHGIDGILHPEPITDLFWVYCILMGSLVSEGATLVVAINELKRSAKENNMSFK 471
            ||||.:|.|||.||||.|:|||:|:..|.|.||||.||||||||||:||||||:|||:....:|.
Mouse   314 VGIFMMGAGLSWYHGIMGLLHPQPMESLLWAYCILAGSLVSEGATLLVAINELRRSAQAKGTTFY 378

  Fly   472 DYVISGKDPCVNVVLCEDAAAVTGVMVAAACMGLSSYTGSPIFDAAGSLVIGALLGAVASFIIYT 536
            .||:..:||..||:|.||.|||.||::||.||||:|.||:|::|:.|||.:|.|||.|::|:|||
Mouse   379 KYVMESRDPSTNVILLEDTAAVLGVIIAATCMGLTSITGNPLYDSLGSLGVGTLLGVVSAFLIYT 443

  Fly   537 NANALVGISIASERLEKINSALEADVMIRAIYDVKGIDIGNARVRYKAELDFDGRELTRSYLDKQ 601
            |..||:|.||..|:::::...||:|..:|||:|||..|:|..:||:|||:|||||.:|||||:||
Mouse   444 NTEALLGRSIQPEQVQRLTELLESDPSVRAIHDVKATDLGLGKVRFKAEVDFDGRVVTRSYLEKQ 508

  Fly   602 DLAKLLTTVRGFQKVEDLESFLLDQGENIVDLMGGEIDRIEMNLRTQFPEIRHVDLEIL 660
            |..:::..::..:..|.||:|:|..||||:|.:|.|:||:|..|:.:.||:||||||||
Mouse   509 DFDQMMQEIQEVKTPEQLEAFMLKHGENIIDTLGAEVDRLEKELKKRNPEVRHVDLEIL 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT49B	NP_725207.1	NTD_ZNT9	214..307	CDD:410964	42/92 (46%)
		FieF	343..655	CDD:439823	175/311 (56%)
Slc30a9	NP_848766.2	NTD_ZNT9	127..214	CDD:410964	42/91 (46%)
		FieF	237..562	CDD:439823	182/324 (56%)
		LXXLL motif. /evidence=ECO:0000250|UniProtKB:Q6PML9	461..465		0/3 (0%)