Protein Alignment ZnT49B and SLC30A9

DIOPT Version :9

• Sequence 1: NP_725207.1
• Gene: ZnT49B / 36393
• FlyBaseID: FBgn0033762
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: XP_016863143.1
• Gene: SLC30A9 / 10463
• HGNCID: 1329
• Length: 591
• Species: Homo sapiens
• Alignment Length: 486
• Identity: 238/486 - (48%)
• Similarity: 321/486 - (66%)
• Gaps: 36/486 - (7%)

  Fly   180 KAGEGIRTSPPAEVTPPAPVIPLKRPRFDYRAS------------LERNFVTPNRAISDFLLTAA 232
            :..|||.|...|         |||:.....|..            .:.||:|..|||::|.|.::
Human    90 ETAEGIGTELKA---------PLKQEPLQVRVKAVLKKREYGSKYTQNNFITGVRAINEFCLKSS 145

  Fly   233 QLESLPKIKRRSPYEQEPPMTVYWRRDVEAKAVEVWGSKENLLRERLKREVERKQYQQIYDSADL 297
            .||.|.||:||||:|.....|||.|.|||||::|||||.|.|.||:..|:....:|::     .|
Human   146 DLEQLRKIRRRSPHEDTESFTVYLRSDVEAKSLEVWGSPEALAREKKLRKEAEIEYRE-----RL 205

  Fly   298 FTVKRRLRDYRREMG-----SRTKVMLDNRKESEKSGQVVATAIAINAANLLFKAGGWLYSGSHS 357
            |..::.||:||..:|     |||..:.     .:..|:||..||.||..|..||...|:|:||.|
Human   206 FRNQKILREYRDFLGNTKPRSRTASVF-----FKGPGKVVMVAICINGLNCFFKFLAWIYTGSAS 265

  Fly   358 MFAEVIHSLADLINQLILAFGIYKSSQSPDIDHPYGYMNMRYVSSLISGVGIFCVGCGLSIYHGI 422
            ||:|.||||:|..||.:||.||.||.|:||..||||:.||||:||||||||||.:|.|||.|||:
Human   266 MFSEAIHSLSDTCNQGLLALGISKSVQTPDPSHPYGFSNMRYISSLISGVGIFMMGAGLSWYHGV 330

  Fly   423 DGILHPEPITDLFWVYCILMGSLVSEGATLVVAINELKRSAKENNMSFKDYVISGKDPCVNVVLC 487
            .|:|||:||..|.|.||||.||||||||||:||:|||:|:|:...|||..||:..:||..||:|.
Human   331 MGLLHPQPIESLLWAYCILAGSLVSEGATLLVAVNELRRNARAKGMSFYKYVMESRDPSTNVILL 395

  Fly   488 EDAAAVTGVMVAAACMGLSSYTGSPIFDAAGSLVIGALLGAVASFIIYTNANALVGISIASERLE 552
            ||.|||.||::||.||||:|.||:|::|:.|||.:|.|||.|::|:||||..||:|.||..|:::
Human   396 EDTAAVLGVIIAATCMGLTSITGNPLYDSLGSLGVGTLLGMVSAFLIYTNTEALLGRSIQPEQVQ 460

  Fly   553 KINSALEADVMIRAIYDVKGIDIGNARVRYKAELDFDGRELTRSYLDKQDLAKLLTTVRGFQKVE 617
            ::...||.|..:|||:|||..|:|..:||:|||:|||||.:|||||:|||..::|..::..:..|
Human   461 RLTELLENDPSVRAIHDVKATDLGLGKVRFKAEVDFDGRVVTRSYLEKQDFDQMLQEIQEVKTPE 525

  Fly   618 DLESFLLDQGENIVDLMGGEIDRIEMNLRTQ 648
            :||:|:|..||||:|.:|.|:||:|..|:.:
Human   526 ELETFMLKHGENIIDTLGAEVDRLEKELKVR 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT49B	NP_725207.1	Cation_efflux	343..542	CDD:279834	122/198 (62%)
SLC30A9	XP_016863143.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141465
Domainoid	1	1.000	269	1.000	Domainoid score	I1861
eggNOG	1	0.900	-	-		E1_COG0053
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4627
Inparanoid	1	1.050	470	1.000	Inparanoid score	I1528
Isobase	1	0.950	-	0	Normalized mean entropy	S3187
OMA	1	1.010	-	-		QHG48079
OrthoDB	1	1.010	-	-		D455459at33208
OrthoFinder	1	1.000	-	-		FOG0006611
OrthoInspector	1	1.000	-	-		oto90964
orthoMCL	1	0.900	-	-		OOG6_104141
Panther	1	1.100	-	-	LDO	PTHR13414
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2191
SonicParanoid	1	1.000	-	-		X4848
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750