DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8778 and Ehhadh

DIOPT Version :9

Sequence 1:	NP_610805.1	Gene:	CG8778 / 36392	FlyBaseID:	FBgn0033761	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_076226.2	Gene:	Ehhadh / 74147	MGIID:	1277964	Length:	718	Species:	Mus musculus

Alignment Length:	194	Identity:	65/194 - (33%)
Similarity:	105/194 - (54%)	Gaps:	20/194 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 ISVIGLNRPAAKNSFSRGMVETFNDVLEDIKKDNGSRVVVLRSLSPGIFCAGADL---KERKGMT 110
            :::|.|..|.. |:.|..::....:.|:....|:..|.:|:...:.. ||||||:   |...|:|
Mouse    11 LAMIRLCNPPV-NAISPTVITEVRNGLQKASLDHTVRAIVICGANDN-FCAGADIHGFKSPTGLT 73

  Fly   111 PEEATEFVKELRGLLIAIEQLPMPVIAAVDGAALGGGLEMALACDIRTAASDTKMGLVETRLAII 175
                      |..|:..|::...||:||:.|.|||||||:||.|..|.|.:..::|..|..|.|:
Mouse    74 ----------LGSLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAKARVGFPEVMLGIL 128

  Fly   176 PGAGGTQRLPRILSPALAKELIFTARVFNGAEAKDLGLVNHVVKQNETQDAAYQQALKLAEEIL 239
            |||.|||.|||::...:|.:||.:.|..:..||..||:::.|||.:..     ::|:|.|:.::
Mouse   129 PGARGTQLLPRVVGVPVALDLITSGRHISTDEALKLGILDVVVKSDPV-----EEAIKFAQTVI 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8778	NP_610805.1	crotonase-like	48..299	CDD:304874	65/194 (34%)
Ehhadh	NP_076226.2	Enoyl-CoA hydratase / isomerase	1..280		65/194 (34%)
		crotonase-like	12..186	CDD:119339	65/190 (34%)
		fadJ	20..702	CDD:236864	62/185 (34%)
		3-hydroxyacyl-CoA dehydrogenase	281..567
		3HCDH_N	297..471	CDD:280833
		3HCDH	473..577	CDD:279114
		3HCDH	614..700	CDD:279114
		Microbody targeting signal. /evidence=ECO:0000250	716..718
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810