DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8778 and Eci3

DIOPT Version :9

Sequence 1:	NP_610805.1	Gene:	CG8778 / 36392	FlyBaseID:	FBgn0033761	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_081223.1	Gene:	Eci3 / 69123	MGIID:	1916373	Length:	317	Species:	Mus musculus

Alignment Length:	295	Identity:	73/295 - (24%)
Similarity:	125/295 - (42%)	Gaps:	27/295 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LARQLAR----PLVASRNLASAAP----------YGDGTEVLVERLDGARQGISVIGLNRPAAKN 61
            |.::.||    .||:|.:.:|.||          ..:..::||...|    ||:.|..|||..||
Mouse    24 LPKETARKNYVDLVSSLSSSSEAPSQGKRGADEKARESKDILVTSED----GITKITFNRPTKKN 84

  Fly    62 SFSRGMVETFNDVLEDIKKDNGSRVVVLRSLSPGIFCAGADLK---ERKGMTPEEATEFVKELRG 123
            :.|..|.......|::...||.  |:.:.:.:...:.:|.|||   ...|...:......|.||.
Mouse    85 AISFQMYLDIMHALKNASTDNS--VITVFTGTGDYYSSGNDLKNLINDAGEIQDVVATSTKILRE 147

  Fly   124 LLIAIEQLPMPVIAAVDGAALGGGLEMALACDIRTAASDTKMGLVETRLAIIPGAGGTQRLPRIL 188
            .:......|.|::|.|:|.|:|..:.:....|...|:.........::|:.||.|..|...|:|:
Mouse   148 FVNCFIDFPKPLVAVVNGPAVGIAVTILALFDAVFASDRATFHTPFSQLSQIPEACSTYMFPKIM 212

  Fly   189 SPALAKELIFTARVFNGAEAKDLGLVNHVVKQNETQDAAYQQALKLAEEILPNGPVGVRMAKLAI 253
            .|..|.|::...:.....||...|||..|..::..:...:.: ||...::.||   .:|::|..|
Mouse   213 GPTKAAEMLLFGKKLTAREAWAQGLVTEVFPESTFETEVWTR-LKTYSKLSPN---VMRISKELI 273

  Fly   254 DKGMQVDLATGYSIEEICYSQVIPTKDRLEGLAAF 288
            .|..:..|.|..:.|.....:.:|.::..:.|..|
Mouse   274 RKHEKQKLYTVNAEECAAALERMPREEYAKALRNF 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8778	NP_610805.1	crotonase-like	48..299	CDD:304874	61/244 (25%)
Eci3	NP_081223.1	ACBP	<2..37	CDD:376410	3/12 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	40..60		3/19 (16%)
		crotonase-like	64..256	CDD:119339	50/198 (25%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:Q05871	120..124		1/3 (33%)
		Microbody targeting signal. /evidence=ECO:0000255	315..317
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810