Protein Alignment CG8778 and ECHDC2

DIOPT Version :10

• Sequence 1: NP_610805.1
• Gene: CG8778 / 36392
• FlyBaseID: FBgn0033761
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_001185890.1
• Gene: ECHDC2 / 55268
• HGNCID: 23408
• Length: 292
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 157/283 - (55%)
• Similarity: 198/283 - (69%)
• Gaps: 2/283 - (0%)

  Fly    17 RPLVASRNLASAAPYGDGTEVLVERLDGARQGISVIGLNRPAAKNSFSRGMVETFNDVLEDIKKD 81
            |||.| |..||....| |:|:.|..|.|..|||:.|.:|||:|:|:.....|....:.|..:::|
Human    12 RPLRA-RGCASDGAAG-GSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLRED 74

  Fly    82 NGSRVVVLRSLSPGIFCAGADLKERKGMTPEEATEFVKELRGLLIAIEQLPMPVIAAVDGAALGG 146
            ...||::.||...|:||||||||||:.|:..|...||:.||||:..|...|.|.|||:||.||||
Human    75 RQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIAAFPAPTIAAMDGFALGG 139

  Fly   147 GLEMALACDIRTAASDTKMGLVETRLAIIPGAGGTQRLPRILSPALAKELIFTARVFNGAEAKDL 211
            |||:|||||:|.|||...|||:||...::|||||||||||.|..|||||||||.|..:|.||..|
Human   140 GLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVL 204

  Fly   212 GLVNHVVKQNETQDAAYQQALKLAEEILPNGPVGVRMAKLAIDKGMQVDLATGYSIEEICYSQVI 276
            |||||.|.|||..|||||:|..||:||||..|:.||:.|:|||:|.:||:|:|.:||.:||:|.|
Human   205 GLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNI 269

  Fly   277 PTKDRLEGLAAFAEKRKPVYKGE 299
            ||:|||||:|||.|||.|.:.|:
Human   270 PTRDRLEGMAAFREKRTPKFVGK 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8778	NP_610805.1	crotonase-like	48..299	CDD:474030	142/250 (57%)
ECHDC2	NP_001185890.1	crotonase-like	38..292	CDD:474030	143/253 (57%)