DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8778 and AUH

DIOPT Version :9

Sequence 1:	NP_610805.1	Gene:	CG8778 / 36392	FlyBaseID:	FBgn0033761	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	XP_005252123.1	Gene:	AUH / 549	HGNCID:	890	Length:	349	Species:	Homo sapiens

Alignment Length:	251	Identity:	152/251 - (60%)
Similarity:	193/251 - (76%)	Gaps:	0/251 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 ISVIGLNRPAAKNSFSRGMVETFNDVLEDIKKDNGSRVVVLRSLSPGIFCAGADLKERKGMTPEE 113
            |.|:|:||...|||.|:.:::..:..::.:|.|...|.:::||..|||||||||||||..|:..|
Human    99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSE 163

  Fly   114 ATEFVKELRGLLIAIEQLPMPVIAAVDGAALGGGLEMALACDIRTAASDTKMGLVETRLAIIPGA 178
            ...||.::|.::..|..||:|.|||:||.|||||||:|||||||.|||..|||||||:||||||.
Human   164 VGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGG 228

  Fly   179 GGTQRLPRILSPALAKELIFTARVFNGAEAKDLGLVNHVVKQNETQDAAYQQALKLAEEILPNGP 243
            ||||||||.:..:|||||||:|||.:|.|||.:||::||::||:..||||::||.||.|.||.||
Human   229 GGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGP 293

  Fly   244 VGVRMAKLAIDKGMQVDLATGYSIEEICYSQVIPTKDRLEGLAAFAEKRKPVYKGE 299
            |.:|:|||||::||:|||.||.:|||.||:|.||||||||||.||.|||.|.||||
Human   294 VAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKGE 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8778	NP_610805.1	crotonase-like	48..299	CDD:304874	150/249 (60%)
AUH	XP_005252123.1	crotonase-like	99..349	CDD:304874	150/249 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148288
Domainoid	1	1.000	308	1.000	Domainoid score	I1347
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1284
Inparanoid	1	1.050	314	1.000	Inparanoid score	I2570
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53571
OrthoDB	1	1.010	-	-		D1123666at2759
OrthoFinder	1	1.000	-	-		FOG0002752
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102410
Panther	1	1.100	-	-	LDO	PTHR11941
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3547
SonicParanoid	1	1.000	-	-		X1838
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800