DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8778 and auh

DIOPT Version :9

Sequence 1:	NP_610805.1	Gene:	CG8778 / 36392	FlyBaseID:	FBgn0033761	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001003576.2	Gene:	auh / 445182	ZFINID:	ZDB-GENE-040801-95	Length:	325	Species:	Danio rerio

Alignment Length:	266	Identity:	170/266 - (63%)
Similarity:	203/266 - (76%)	Gaps:	0/266 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 GTEVLVERLDGARQGISVIGLNRPAAKNSFSRGMVETFNDVLEDIKKDNGSRVVVLRSLSPGIFC 98
            |.:::|..|||...||.|:|:|||.|||:.|:.:|...::.||.:|.||..|.|:|.|:.|||||
Zfish    60 GDDLIVRYLDGDDSGIVVMGINRPEAKNAISKNLVSMMSEALESMKTDNTVRTVILCSMVPGIFC 124

  Fly    99 AGADLKERKGMTPEEATEFVKELRGLLIAIEQLPMPVIAAVDGAALGGGLEMALACDIRTAASDT 163
            ||||||||..|...|...||.:.|.|:..:..||||.|||:||||||||||||||||||.||:..
Zfish   125 AGADLKERAKMQQSEVGPFVTKARTLISELGALPMPTIAAIDGAALGGGLEMALACDIRVAANSA 189

  Fly   164 KMGLVETRLAIIPGAGGTQRLPRILSPALAKELIFTARVFNGAEAKDLGLVNHVVKQNETQDAAY 228
            |||||||:|||||||||||||||.:..::||||||.|||.||.|||.||||||.|:||:..||||
Zfish   190 KMGLVETKLAIIPGAGGTQRLPRTVGVSIAKELIFAARVLNGEEAKSLGLVNHAVEQNKGGDAAY 254

  Fly   229 QQALKLAEEILPNGPVGVRMAKLAIDKGMQVDLATGYSIEEICYSQVIPTKDRLEGLAAFAEKRK 293
            .:||.||.|.:|.||:.||||||||::|::|||.||.:|||.|||||||||||||||.||.|||.
Zfish   255 LRALDLAREFIPQGPIAVRMAKLAINQGIEVDLKTGLAIEEACYSQVIPTKDRLEGLLAFKEKRP 319

  Fly   294 PVYKGE 299
            |.:|||
Zfish   320 PRFKGE 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8778	NP_610805.1	crotonase-like	48..299	CDD:304874	163/250 (65%)
auh	NP_001003576.2	crotonase-like	71..325	CDD:304874	163/253 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582205
Domainoid	1	1.000	322	1.000	Domainoid score	I1201
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1284
Inparanoid	1	1.050	334	1.000	Inparanoid score	I2403
OMA	1	1.010	-	-		QHG53571
OrthoDB	1	1.010	-	-		D1123666at2759
OrthoFinder	1	1.000	-	-		FOG0002752
OrthoInspector	1	1.000	-	-		oto40645
orthoMCL	1	0.900	-	-		OOG6_102410
Panther	1	1.100	-	-	LDO	PTHR11941
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3547
SonicParanoid	1	1.000	-	-		X1838
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800