DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8778 and echdc2

DIOPT Version :9

Sequence 1:	NP_610805.1	Gene:	CG8778 / 36392	FlyBaseID:	FBgn0033761	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_997953.1	Gene:	echdc2 / 338247	ZFINID:	ZDB-GENE-030219-147	Length:	301	Species:	Danio rerio

Alignment Length:	293	Identity:	152/293 - (51%)
Similarity:	200/293 - (68%)	Gaps:	1/293 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ASGLARQLAR-PLVASRNLASAAPYGDGTEVLVERLDGARQGISVIGLNRPAAKNSFSRGMVETF 71
            |..:.|.|.| ....:|:..|.....|..||.:.||:|...||..:.:.|..|:||.....|...
Zfish     9 AGPIKRLLPRGSFTQTRSWCSHGSVSDKKEVRLNRLEGDDNGIVEVLMCRERARNSLGHVFVGQM 73

  Fly    72 NDVLEDIKKDNGSRVVVLRSLSPGIFCAGADLKERKGMTPEEATEFVKELRGLLIAIEQLPMPVI 136
            .|::..::.|:..||:|.|||.||:||||||||||..|:..||..||..||.|:..|..||||.|
Zfish    74 RDLVSSLQHDSAVRVLVFRSLIPGVFCAGADLKERAQMSNAEAELFVHGLRSLMNDIAALPMPTI 138

  Fly   137 AAVDGAALGGGLEMALACDIRTAASDTKMGLVETRLAIIPGAGGTQRLPRILSPALAKELIFTAR 201
            |||||.|||||||:|||||:||||...:|||:||...::|||||:|||||.:..|:|||||||.|
Zfish   139 AAVDGFALGGGLELALACDLRTAAHCAQMGLIETTRGLLPGAGGSQRLPRTVGFAVAKELIFTGR 203

  Fly   202 VFNGAEAKDLGLVNHVVKQNETQDAAYQQALKLAEEILPNGPVGVRMAKLAIDKGMQVDLATGYS 266
            ...|.:|.:|||||..|.||:|.|||:::||.||.||||..|:.|||||:|:::|.:||:::|.:
Zfish   204 RVGGEQAVNLGLVNRSVPQNQTGDAAHREALSLAREILPQAPIAVRMAKVAMNRGAEVDISSGMA 268

  Fly   267 IEEICYSQVIPTKDRLEGLAAFAEKRKPVYKGE 299
            ||.:||:::|||:||.||:|||.|||.|.|.||
Zfish   269 IEGMCYARLIPTRDRQEGMAAFIEKRPPRYTGE 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8778	NP_610805.1	crotonase-like	48..299	CDD:304874	138/250 (55%)
echdc2	NP_997953.1	crotonase-like	47..301	CDD:304874	138/253 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582203
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53571
OrthoDB	1	1.010	-	-		D1123666at2759
OrthoFinder	1	1.000	-	-		FOG0002752
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102410
Panther	1	1.100	-	-	O	PTHR11941
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3547
SonicParanoid	1	1.000	-	-		X1838
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.750