Protein Alignment CG8778 and ECHS1

DIOPT Version :10

• Sequence 1: NP_610805.1
• Gene: CG8778 / 36392
• FlyBaseID: FBgn0033761
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_004083.3
• Gene: ECHS1 / 1892
• HGNCID: 3151
• Length: 290
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 96/288 - (33%)
• Similarity: 151/288 - (52%)
• Gaps: 18/288 - (6%)

  Fly    17 RPLV---ASRNLASAAPYGDGTEVLVERLDGARQGISVIGLNRPAAKNSFSRGMVETFNDVLEDI 78
            ||.|   |.|..||.|.:    |.::....|....:.:|.||||.|.|:...|:::..|..|:..
Human    16 RPPVRCPAWRPFASGANF----EYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTF 76

  Fly    79 KKDNGSRVVVLRSLSPGIFCAGADLKERKGMTPEE--ATEFVKELRGLLIAIEQLPMPVIAAVDG 141
            ::|.....:||.. ....|.||||:||.:.::.::  :::|:|....|    .|:..||||||:|
Human    77 EEDPAVGAIVLTG-GDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHL----TQVKKPVIAAVNG 136

  Fly   142 AALGGGLEMALACDIRTAASDTKMGLVETRLAIIPGAGGTQRLPRILSPALAKELIFTARVFNGA 206
            .|.|||.|:|:.|||..|....:....|..:..||||||||||.|.:..:||.|::.|....:..
Human   137 YAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQ 201

  Fly   207 EAKDLGLVNHVVKQNETQDAAYQQALKLAEEILPNGPVGVRMAKLAIDKGMQVDLATGYSIEEIC 271
            :||..|||:.:.    ..:...::|::.||:|..|..:.|.|||.:::...::.|..|..:|:..
Human   202 DAKQAGLVSKIC----PVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKL 262

  Fly   272 YSQVIPTKDRLEGLAAFAEKRKPVYKGE 299
            :.....|.||.||:.||.||||..:|.:
Human   263 FYSTFATDDRKEGMTAFVEKRKANFKDQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8778	NP_610805.1	crotonase-like	48..299	CDD:474030	86/252 (34%)
ECHS1	NP_004083.3	crotonase-like	32..288	CDD:474030	87/268 (32%)