DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8778 and ech-1.1

DIOPT Version :9

Sequence 1:	NP_610805.1	Gene:	CG8778 / 36392	FlyBaseID:	FBgn0033761	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_506810.1	Gene:	ech-1.1 / 180037	WormBaseID:	WBGene00001150	Length:	755	Species:	Caenorhabditis elegans

Alignment Length:	288	Identity:	79/288 - (27%)
Similarity:	143/288 - (49%)	Gaps:	33/288 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSMLIKRASGLARQLARPLVASRNLASAAPYGDGTEVLVERLDGARQG-ISVIGLNRP-AAKNSF 63
            :|.::.|:|.:.|     ...|..|.|.:.:...:...||     :|| ::|:.::.| ..:|..
Worm     2 LSRVVHRSSSVFR-----TNLSFRLFSQSAFAVHSTHRVE-----KQGDVAVMKIDLPNTTENVL 56

  Fly    64 SRGMVETFNDVLEDIKKDNGSRVVVLRSLSPGIFCAGADLKERKG-MTPEEATEFVKELRGLLIA 127
            ::.:....|:.|:.::.|...:.:|:.|..|..|.||||::..|. .|....:..::|.:..|:.
Worm    57 NKALFAEMNETLDRLQSDQSVKAIVVMSGKPNSFVAGADIQMFKAEKTAAGVSNLLREGQKQLLT 121

  Fly   128 IEQLPMPVIAAVDGAALGGGLEMALACDIRTAASDTK--MGLVETRLAIIPGAGGTQRLPRILSP 190
            ||....|::||:.|:.:|||||:||||..|.|.:|.|  :||.|..|.|:||.|||||||::.:.
Worm   122 IELSQKPIVAAIMGSCMGGGLEIALACHYRIAVNDKKTLLGLPEVTLGIMPGDGGTQRLPKLTTV 186

  Fly   191 ALAKELIFTARVFNGAEAKDLGLVNHVVK--------QNET-----QDAAYQQALKLAEEILPNG 242
            ....:|..|.:.....:|..:|:|:.|::        ..||     ::.|.|.|.:||     ||
Worm   187 QNVLDLTLTGKRIKANKAMKIGIVDRVIQPLGDGICTSTETTHKYLEEIAVQSARELA-----NG 246

  Fly   243 PVGVRMAKLAIDKGMQVDLATGYSIEEI 270
            .:.:...|..:....|..:.:.:.::.:
Worm   247 KLKINRDKGFVHNATQAVMTSKFVLDNV 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8778	NP_610805.1	crotonase-like	48..299	CDD:304874	69/241 (29%)
ech-1.1	NP_506810.1	fa_ox_alpha_mit	20..754	CDD:131494	74/265 (28%)
		crotonase-like	34..216	CDD:119339	61/186 (33%)
		3HCDH_N	355..533	CDD:280833
		3HCDH	535..630	CDD:279114
		3HCDH	668..754	CDD:279114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810