DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8778 and ech-1.2

DIOPT Version :9

Sequence 1:	NP_610805.1	Gene:	CG8778 / 36392	FlyBaseID:	FBgn0033761	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_491789.1	Gene:	ech-1.2 / 172310	WormBaseID:	WBGene00020347	Length:	781	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	86/301 - (28%)
Similarity:	148/301 - (49%)	Gaps:	28/301 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSMLIKRASGLARQLARPLVASRNLASAAPYGDGTEVLVERLDGARQG-ISVIGLNRPAAK-NSF 63
            :|.|:.::|    ...|..::.|..:.:||....|    .|::  :|| ::|:.::.|..| |..
Worm    28 LSRLVHQSS----STLRTNLSFRLFSQSAPAMQTT----HRVE--KQGDVAVVKIDLPNTKENVL 82

  Fly    64 SRGMVETFNDVLEDIKKDNGSRVVVLRSLSPGIFCAGADLKERKGMTPEEATEFV-KELRGLLIA 127
            ::.:.......|:.::.|...:.:|:.|..|..|.||||::..|......|||.: :|.:.....
Worm    83 NKALFAEMKATLDKLQSDESIKSIVVMSGKPNSFVAGADIQMIKAEGTATATETLSREGQEQFFR 147

  Fly   128 IEQLPMPVIAAVDGAALGGGLEMALACDIRTAASDTK--MGLVETRLAIIPGAGGTQRLPRILSP 190
            ||:...||:||:.|:.:|||||:||||..|.|.:|.|  :.|.|..|.::||||||||||::.:.
Worm   148 IEKSQKPVVAAIMGSCMGGGLELALACHYRIAVNDKKTLLSLPEVMLGLLPGAGGTQRLPKLTTV 212

  Fly   191 ALAKELIFTARVFNGAEAKDLGLVNHVVK---------QNETQDAAYQQALKLAEEILPNGPVGV 246
            ....:|..|.:.....:||.:|:|:.|::         ...|.....:.|:|.|:| |.||.:.:
Worm   213 QNVLDLTLTGKKIKADKAKKIGIVDRVIQPLGDGLGPAAENTHKYLEEIAVKAAQE-LANGKLKI 276

  Fly   247 RMAKLAIDKGMQVDLATGYSIEEICYSQVIPTKDRLEGLAA 287
            ...|..:.|..|..:.....::.:....   .||:|..|.|
Worm   277 NRDKGFMHKATQAVMTNSLFLDNVVLKM---AKDKLMKLTA 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8778	NP_610805.1	crotonase-like	48..299	CDD:304874	76/254 (30%)
ech-1.2	NP_491789.1	fa_ox_alpha_mit	46..780	CDD:131494	82/279 (29%)
		crotonase-like	60..269	CDD:119339	67/211 (32%)
		3HCDH_N	381..559	CDD:280833
		3HCDH	561..656	CDD:279114
		3HCDH	694..780	CDD:279114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910