Protein Alignment CG8778 and Cdyl

DIOPT Version :10

• Sequence 1: NP_610805.1
• Gene: CG8778 / 36392
• FlyBaseID: FBgn0033761
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_034011.1
• Gene: Cdyl / 12593
• MGIID: 1339956
• Length: 593
• Species: Mus musculus
• Alignment Length: 247
• Identity: 59/247 - (23%)
• Similarity: 103/247 - (41%)
• Gaps: 24/247 - (9%)

  Fly    23 RNLASAAPYGDGTEVLVERLDGARQGISVIGLNRPAAKNSFSRGMVETFNDVLEDIKKDNGSRVV 87
            |...||..|.|   ::|.:.||...   ::...:.:..||.:..:::.....|.....|: |::|
Mouse   328 RQTESAYRYRD---IVVRKQDGFTH---ILLSTKSSENNSLNPEVMKEVQSALSTAAADD-SKLV 385

  Fly    88 VLRSLSPGIFCAGADL--------KERKGMTPEEATEFVKELRGLLIAIEQLPMPVIAAVDGAAL 144
            :|.::. .:||.|.|.        .:||    .|:|:....:|..:....|...|:|.||:|.|:
Mouse   386 LLSAVG-SVFCCGLDFIYFIRRLTDDRK----RESTKMADAIRNFVNTFIQFKKPIIVAVNGPAI 445

  Fly   145 GGGLEMALACDIRTAASDTKMGLVETRLAIIPGAGGTQRLPRILSPALAKELIFTARVFNGAEAK 209
            |.|..:...||:..|..........|.....|....|...|:|:..|.|.|::|:.|.....||.
Mouse   446 GLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLFSGRKLTAQEAC 510

  Fly   210 DLGLVNHVVKQNETQDAAYQQALKLAEEILPNGPVGVRMAKLAIDKGMQVDL 261
            ..|||:.|.    ......|:.:...:|:....||.:..:|..:...|:::|
Mouse   511 GKGLVSQVF----WPGTFTQEVMVRIKELASCNPVVLEESKALVRCNMKMEL 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8778	NP_610805.1	crotonase-like	48..299	CDD:474030	51/222 (23%)
Cdyl	NP_034011.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		Interaction with EZH2. /evidence=ECO:0000250|UniProtKB:Q9Y232	56..304
		CD_CDY	57..106	CDD:349284
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..158
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..223
		crotonase-like	339..535	CDD:119339	48/208 (23%)
		Acetyl-CoA-binding domain. /evidence=ECO:0000255	357..589		51/212 (24%)