DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8778 and echdc2

DIOPT Version :9

Sequence 1:	NP_610805.1	Gene:	CG8778 / 36392	FlyBaseID:	FBgn0033761	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001107379.1	Gene:	echdc2 / 100135206	XenbaseID:	XB-GENE-948250	Length:	294	Species:	Xenopus tropicalis

Alignment Length:	299	Identity:	166/299 - (55%)
Similarity:	216/299 - (72%)	Gaps:	5/299 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSMLIKRASGLARQLARPLVASRNLASAAPYGDGTEVLVERLDGARQGISVIGLNRPAAKNSFSR 65
            |..|::...|:.|.|...:.|.|.|:|.|     :||...||||:.:||:.|.::||.|:||..:
Frog     1 MGSLVRLLVGVQRALPGSVWAVRRLSSGA-----SEVYAARLDGSNEGIAEIIMSRPHARNSLGK 60

  Fly    66 GMVETFNDVLEDIKKDNGSRVVVLRSLSPGIFCAGADLKERKGMTPEEATEFVKELRGLLIAIEQ 130
            ..|..|.|.::.::.|:..||||::|..|||||||||||||..|...|.:.||::||.|:..|..
Frog    61 VFVSEFFDTVDSLRHDSSVRVVVVKSSIPGIFCAGADLKERAQMDNAEVSLFVQQLRKLMSEIAA 125

  Fly   131 LPMPVIAAVDGAALGGGLEMALACDIRTAASDTKMGLVETRLAIIPGAGGTQRLPRILSPALAKE 195
            ||||.||||||.|||||||:|||||:|.|||..||||:||...::|||||:|||||:|...||||
Frog   126 LPMPTIAAVDGFALGGGLELALACDLRVAASSAKMGLIETTRGLLPGAGGSQRLPRLLGIGLAKE 190

  Fly   196 LIFTARVFNGAEAKDLGLVNHVVKQNETQDAAYQQALKLAEEILPNGPVGVRMAKLAIDKGMQVD 260
            ||||.|..:|.||:.:||||..|.|||..||||.:||:||:||||..||.|||||||:::|::||
Frog   191 LIFTGRQIDGTEAQHIGLVNDAVPQNEEGDAAYLRALELAQEILPQAPVAVRMAKLAMNRGIEVD 255

  Fly   261 LATGYSIEEICYSQVIPTKDRLEGLAAFAEKRKPVYKGE 299
            :|:|.:||.:||.|||||||||||::||.|||:|.|.|:
Frog   256 IASGMAIEAMCYGQVIPTKDRLEGMSAFREKRQPHYTGK 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8778	NP_610805.1	crotonase-like	48..299	CDD:304874	149/250 (60%)
echdc2	NP_001107379.1	crotonase-like	40..294	CDD:304874	149/253 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1123666at2759
OrthoFinder	1	1.000	-	-		FOG0002752
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3547
SonicParanoid	1	1.000	-	-		X1838
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040