DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8785 and Slc38a6

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001032806.2	Gene:	Slc38a6 / 625098	MGIID:	3648156	Length:	457	Species:	Mus musculus

Alignment Length:	485	Identity:	109/485 - (22%)
Similarity:	193/485 - (39%)	Gaps:	123/485 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 EKELSLTDDPYHPFEHRDP-----NGASAGGALAHLLKSSLGTGILAMPMAFHNAGLAFGMAMTL 101
            :.|.::..|.:.|....:|     :|||.|.::.:::.:.:|:|||.:.....|.|:.....:.|
Mouse    20 QPEEAVAADEWSPLLSNEPHRQGSSGASFGLSVFNVMNAIMGSGILGLAYVMANTGILGFSFLLL 84

  Fly   102 IVGFLCTHCVHILVKTSHDICRDAKVSA---LGFAETAEKVFEYGPKGMRPYSNFAKQFV----- 158
            .|..|.::.||:|:.    :|....|::   ||       :|.:|..|        |..|
Mouse    85 FVALLASYSVHLLLA----MCIHTAVTSYEDLG-------LFAFGLPG--------KVVVAGTII 130

  Fly   159 --DIGLMATYY--------AA-----------------------ACVYIVFIATSFHDV--INYD 188
              :||.|::|.        ||                       .||.|||..:....:  :.|.
Mouse   131 IQNIGAMSSYLLIIKTELPAAISEFLPSDHSGSWYLDGQMLLIIICVGIVFPLSLLPKIGFLGYT 195

  Fly   189 LKINWDVRIYIALTVIPCLLIGQIRDLKWLVPFSMMANIFIVVTFAIT---------LYYMFDEP 244
            ..:::...::.||.|:       |:  ||.||..:..:. |...|.|:         |:: |.:.
Mouse   196 SSLSFFFMVFFALVVV-------IK--KWAVPCPVTLDC-INEVFQISNATDDCKPKLFH-FSKE 249

  Fly   245 LVYSDKPLIAKAAHIPLFFATVIFAMEGIGVVMPVENSMRKPQHFLGCPGVLNIAMVTVVSLYAI 309
            .||:          ||    |:.|:......|:|:...::.|.. .....|.|.|:.....:|.:
Mouse   250 SVYA----------IP----TMAFSFLCHTSVLPIYCELQSPSK-KRMQNVTNTAIALSFLVYFV 299

  Fly   310 IGFFGYVRFGDQVRGSI----TLNLPEGAWLGDTAKLLMAVAILFTFGLQFYVPNEILWRKI--S 368
            ...|||:.|.|:|...:    :..||... :....||.:..|:|.|..|..:...:.|...:  :
Mouse   300 SALFGYLTFYDKVESELLQGYSKYLPHDV-IVMAVKLCILFAVLLTAPLIHFPARKALMMILFSN 363

  Fly   369 HKFSPEKHNITQILLRSGIILLSGGVAAAIPNLEPFISLVGAVFFSLLGIFVPSFVETVYLWPDR 433
            :.||..:|::|...|.:.|::|    |..:|::.....:|||...:.| |||  |....||...|
Mouse   364 YPFSWIRHSLTTAALNAIIVVL----AIYVPDIRNVFGVVGASTSTCL-IFV--FPGLFYLKLSR 421

  Fly   434 LGVCKWKLVKNIFL-------GVFSILALV 456
            .....||.:..:||       |.||::.::
Mouse   422 EDFLSWKKLGALFLLLTGAVVGSFSLVLII 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	106/467 (23%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	105/460 (23%)
Slc38a6	NP_001032806.2	SdaC	45..452	CDD:223884	105/460 (23%)
Slc38a6	NP_001032806.2	SLC5-6-like_sbd	45..452	CDD:294310	105/460 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820