DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8785 and slc36a1

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	XP_021336836.1	Gene:	slc36a1 / 559308	ZFINID:	ZDB-GENE-061117-1	Length:	468	Species:	Danio rerio

Alignment Length:	468	Identity:	150/468 - (32%)
Similarity:	231/468 - (49%)	Gaps:	46/468 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 DFNSKANLTEKELSLTDDPYHPFEHRDPNGASAGG--------ALAHLLKSSLGTGILAMPMAFH 89
            ||:.:     .|....|:|.|....|.......||        .:.||||.::|||:|.:|:|..
Zfish    12 DFSRR-----DESPTEDEPIHSPGSRQTEYERIGGRTGSSVLQTIIHLLKGNIGTGLLGLPLAVR 71

  Fly    90 NAGLAFGMAMTLIVGFLCTHCVHILVKTSHDICRDAKVSALGFAETAEKVFEYGPKG---MRPYS 151
            ||||..|....||:|.:..||:::|||.:|.:........|.:.:..    |||.:.   :..:|
Zfish    72 NAGLLVGPLSLLIMGIVAVHCMNLLVKCAHHLSAKLGKPFLSYGDAV----EYGMENVSWLSRHS 132

  Fly   152 NFAKQFVDIGLMATYYAAACVYIVFIATSFHDVI-----------NYDLKI---NWDVRIYIALT 202
            .:.:..|::.|..|.....|||.||::.:...|:           |.:..:   ::|.|:|:...
Zfish   133 IWGRHVVNLFLNITQLGFCCVYFVFLSDNVKQVVETANATTGNCHNNETAVPVPSYDSRLYMVFF 197

  Fly   203 VIPCLLIGQIRDLKWLVPFSMMANIFIVVTFAITLYYM---FDEPLVYSDKPLIAKAAHIPLFFA 264
            :...:|:..||:||:|.|.|..|||.:..:..:..||.   ...|:   :.||..:.|..||||.
Zfish   198 LPFIILLVFIRNLKYLAPLSFAANICMCASLVLIYYYCLTNIPNPI---NLPLAGRGADYPLFFG 259

  Fly   265 TVIFAMEGIGVVMPVENSMRKPQHFLGCPGVLNIAMVTVVSLYAIIGFFGYVRFGDQVRGSITLN 329
            |.|||.||||||:|:||.|:.|::|   ..||.:.|..|..||..:|..||:.||:::|||||||
Zfish   260 TAIFAFEGIGVVLPLENKMQNPRNF---TKVLYLGMGIVTFLYISLGTIGYIGFGEEIRGSITLN 321

  Fly   330 LPEGAWLGDTAKLLMAVAILFTFGLQFYVPNEILWRKISHKFSPEKHNITQILLRSGIILLSGGV 394
            ||. .||....|||.:..|..|:.|||||..|||......:..|....:..:.:|..::.|:..:
Zfish   322 LPL-CWLYQIVKLLYSFGIYITYALQFYVSAEILIPPAVARCGPRWALMVDLSIRVALVGLTCAL 385

  Fly   395 AAAIPNLEPFISLVGAVFFSLLGIFVPSFVETVYLWPDRLGVCKWKLVKNIFLGVFSILALVAGA 459
            |..||.|:..|||||:|..|.|.:.:|..::.:....:.:.  .|...|:|.:.|...:..:||.
Zfish   386 AILIPELDLVISLVGSVSSSALALIIPPLLQIITFHNEDMK--PWVFAKDILISVLGFVGFIAGT 448

  Fly   460 VASINEIIEMYSD 472
            ..||.||:....|
Zfish   449 YTSIQEIVARNGD 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	136/424 (32%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	138/428 (32%)
slc36a1	XP_021336836.1	SLC5-6-like_sbd	44..453	CDD:320982	137/421 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	7.030