Protein Alignment CG8785 and SLC38A4

DIOPT Version :10

• Sequence 1: NP_610804.1
• Gene: CG8785 / 36391
• FlyBaseID: FBgn0033760
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_060488.2
• Gene: SLC38A4 / 55089
• HGNCID: 14679
• Length: 547
• Species: Homo sapiens
• Alignment Length: 599
• Identity: 123/599 - (20%)
• Similarity: 219/599 - (36%)
• Gaps: 196/599 - (32%)

  Fly     4 NKGFTPDGQESL-PSAP-------TVENPPPYTNAIND------FNSKANLTEKELSLTDDPYHP 54
            |....||.:.|. .|||       ..|.....:...|:      |.:...|.:|:|:...|.:|
Human     8 NVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGKKKLADYADEHH- 71

  Fly    55 FEHRDPNGASAGGALAHLLKSSLGTGILAMPMAFHNAGLAFGMAMTLIVGFLCTHCVHILVKTSH 119
                 |...|.|.:..:|..:.:|:|||.:..|..|.|:...:.|.|.|..|..:.||:|:||:.
Human    72 -----PGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAK 131

  Fly   120 DICRDAKVSALGFAETAEKVFEYGPKGMRPYSNFAKQFVDIGLMATYYAAACVYIVFIATSFHDV 184
            :      ..:|.:.:..||.|.: |..:..:.:...|  :||.|::       |:..|.....:|
Human   132 E------GGSLIYEKLGEKAFGW-PGKIGAFVSITMQ--NIGAMSS-------YLFIIKYELPEV 180

  Fly   185 INYDLKI-----NWDVR-----IYIALTVI-PCLLIGQIRDLKWLVPFSMMANIFIVVTFAITLY 238
            |...:.:     .|.:.     |::::.:| |..|:..:..|.:...||:...:|.|   ::.:|
Human   181 IRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFV---SVVIY 242

  Fly   239 YMFDEP------------LVYSDK-PL-------------------------------------- 252
            ..|..|            |.:::. |:
Human   243 KKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLH 307

  Fly   253 ---IAKAAHI-----PLFFA----------TVIFAMEGIGVVMPV-----ENSMRKPQHFLGCPG 294
               :...||.     |.:|.          .::||......|:|:     :.|.||.|      .
Human   308 DSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQ------T 366

  Fly   295 VLNIAMVTVVSLYAIIGFFGYVRFGDQVRGSI--------TLNLPEGAWLGDTAKLLMA-----V 346
            |.||::..::.:|.:...|||:.|..:|...:        ||::|          |||.     |
Human   367 VSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIP----------LLMVRLAVLV 421

  Fly   347 AILFTFGLQFYVPN----EILWRKISHKFSPEKHNITQILLRSGIILLSGGVAAAIPNLEPFISL 407
            |:..|..:..:...    .:|:.|  ..||..:|    .|:.:.:|.|:..:...:|.::.....
Human   422 AVTLTVPIVLFPIRTSVITLLFPK--RPFSWIRH----FLIAAVLIALNNVLVILVPTIKYIFGF 480

  Fly   408 VGAVFFSLLGIFVPSFVETVYLWPDRLGVCKWKLVKN------------IFL--GVFSILALVAG 458
            :||...::|...:|:   ..||          ||||.            |||  |:|.::    |
Human   481 IGASSATMLIFILPA---VFYL----------KLVKKETFRSPQKVGALIFLVVGIFFMI----G 528

  Fly   459 AVASINEIIEMYSD 472
            ::|.|  ||:...|
Human   529 SMALI--IIDWIYD 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:444915	103/516 (20%)
SLC38A4	NP_060488.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		7/21 (33%)
		SLC5-6-like_sbd	73..535	CDD:444915	104/521 (20%)