Protein Alignment CG8785 and SLC38A2

DIOPT Version :9

• Sequence 1: NP_610804.1
• Gene: CG8785 / 36391
• FlyBaseID: FBgn0033760
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_061849.2
• Gene: SLC38A2 / 54407
• HGNCID: 13448
• Length: 506
• Species: Homo sapiens
• Alignment Length: 519
• Identity: 102/519 - (19%)
• Similarity: 191/519 - (36%)
• Gaps: 163/519 - (31%)

  Fly    33 DFNSKANLTEKELSLTDDPYHPFEHRDPNGASAGGALAHLLKSSLGTGILAMPMAFHNAGLAFGM 97
            :|..::||.:|:.   :..:|      |...|.|.::.:|..:.:|:|||.:..|..|.|:|..:
Human    50 NFLLESNLGKKKY---ETEFH------PGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFI 105

  Fly    98 AMTLIVGFLCTHCVHILVKTSHDICRDAKVSALGFAETAEKVFEYGPKGMRPYSNFAKQFVDIGL 162
            .:...|.....:.||:|:||:::      ..:|.:.:...|.|  |..|....|. :....:||.
Human   106 ILLTFVSIFSLYSVHLLLKTANE------GGSLLYEQLGYKAF--GLVGKLAASG-SITMQNIGA 161

  Fly   163 MATYYAAACVYIVFIATSFHDVINYDLKI-------------------NWDVRIYIALTVIPCLL 208
            |::|        :||       :.|:|.:                   |:.|.:...:.::|..|
Human   162 MSSY--------LFI-------VKYELPLVIQALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSL 211

  Fly   209 IGQIRDL---------------------KWLVPFSMMANIFIVVTFAITL--------------- 237
            ...:..|                     |:.||..:.|.:.|..|...||
Human   212 FRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPALSHNVT 276

  Fly   238 --------YYMFDEPLVYSDKPLIAKAAHIPLFFATVIFAMEGIGVVMPV-----ENSMRKPQHF 289
                    |::|:...||:          :|:    :||:......|:|:     :.|.|:..:
Human   277 ENDSCRPHYFIFNSQTVYA----------VPI----LIFSFVCHPAVLPIYEELKDRSRRRMMN- 326

  Fly   290 LGCPGVLNIAMVTVVSLYAIIGFFGYVRFGDQVRGSITLNLPEGAWLG-DTAKLLMAVAILFTFG 353
                 |..|:...:..:|.:...|||:.|.:.|...:....  .:.|| |...|::.:|:|....
Human   327 -----VSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTY--SSILGTDILLLIVRLAVLMAVT 384

  Fly   354 LQFYVPNEILWRKISHKFSPEKHNITQILLRS-------------GIILLSGGVAAAIPNLEPFI 405
            |.  ||..|.         |.:.::|.:|..|             .|:..:..:...:|.:....
Human   385 LT--VPVVIF---------PIRSSVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVPTIRDIF 438

  Fly   406 SLVGAVFFSLLGIFVPS--FVETVYLWPDRLGVCKWKLVKNI----FLGVFSILALVAGAVASI 463
            ..:||...|:|...:||  :::.|...|       .|.|:.|    ||  .|.:.::.|::|.|
Human   439 GFIGASAASMLIFILPSAFYIKLVKKEP-------MKSVQKIGALFFL--LSGVLVMTGSMALI 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	94/484 (19%)
		SLC5-6-like_sbd	62..463	CDD:294310	95/488 (19%)
SLC38A2	NP_061849.2	Regulates protein turnover upon amino acid deprivation. /evidence=ECO:0000250	1..96		13/54 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		SLC5-6-like_sbd	69..495	CDD:320982	96/491 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820