DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8785 and slc38a6

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001008117.2	Gene:	slc38a6 / 493479	XenbaseID:	XB-GENE-1016511	Length:	448	Species:	Xenopus tropicalis

Alignment Length:	479	Identity:	102/479 - (21%)
Similarity:	185/479 - (38%)	Gaps:	94/479 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 NAINDFNSKANLTEKELSLTDDPYHPFEHRDPNGASAGGALAHLLKSSLGTGILAMPMAFHNAGL 93
            |.::.....|...|....|.:.|    :.|...|.|.|.|:.:|:.:.:|:|||.:..|....|:
Frog     9 NTLDGHQVSAGRDESTPLLANSP----QRRSSGGTSFGFAVFNLMNAIMGSGILGLSYAMAKTGI 69

  Fly    94 AFGMAMTLIVGFLCTHCVHILVKTSHDICRDAKVSALGFAETAEKVFEYGPKGMRPYSNFAKQFV 158
            ....|:.|||..|..:.:|:|::    :|....|::            |...|:..:....|..|
Frog    70 LGFSALLLIVALLAAYSIHLLLR----MCLLTAVTS------------YEDLGLYAFGRSGKVLV 118

  Fly   159 DIGLMATYYAAACVYIVFIATSFHDVINYDLK----INW--DVRIYIALTVIPCLLIGQIRDLKW 217
            ...::.....|...|:..|.:.....|...|.    ..|  |.|..:.:|.: |:::
Frog   119 ACTILIQNVGAMSSYLFIIKSELPAAIASFLPGAQGEPWYLDGRTLLIITSV-CIVL-------- 174

  Fly   218 LVPFSMMANI-FIVVTFAITLYYMFDEPLVYSDKPLIAKAAHIP--------------------- 260
              |.:::..| |:..|.:::.::|     ||....::.|..:||
Frog   175 --PLALLPKIGFLGYTSSLSFFFM-----VYFAVVIVIKKWNIPCPLPPLNHTVTFLQAPNISEC 232

  Fly   261 ---LF-------FA--TVIFAMEGIGVVMPVENSMRKPQHFLGCPGVLNIAMVTVVSLYAIIGFF 313
               ||       ||  |:.|:......|:|:...::.|.. .....|.|:.:.....:|.|...|
Frog   233 KPKLFDFSKESAFALPTMAFSFLCHTSVLPIYCELKSPSK-SKMQNVANVGIALSFLIYYISALF 296

  Fly   314 GYVRFGDQVRGSI----TLNLPEGAWLGDTAKLLMAVAILFTFGL-QFYVPNEILWRKIS-HKFS 372
            ||:.|.|.|:..:    :..||:.. |..|.:|.:.:|:|.|..| .|.....::....| :.||
Frog   297 GYLTFYDNVKSELLQGYSKYLPKDV-LIITVRLCILLAVLLTVPLIHFPARKAVMMMFFSRYPFS 360

  Fly   373 PEKHNITQILLRSGIILLSGGVAAAIPNLEPFISLVGA-----VFFSLLGIFVPSFVETVYLWPD 432
            ..:|.:..::|...|:||    |..:|::.....:||:     :.|...|:|...........|.
Frog   361 YIRHILVTLVLNIIIVLL----AIYVPDMRSVFGVVGSTTSTCLLFVFPGLFYVKLGREDCSSPQ 421

  Fly   433 RLGVCKWKLVKNIFLGVFSILALV 456
            :.|.| ..||..|.:|..|:..::
Frog   422 KFGAC-GLLVLGICIGACSLTLII 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	96/448 (21%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	96/446 (22%)
slc38a6	NP_001008117.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36		6/30 (20%)
slc38a6	NP_001008117.2	SLC5-6-like_sbd	37..412	CDD:382020	88/412 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920