DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8785 and polyph

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_610631.1	Gene:	polyph / 36161	FlyBaseID:	FBgn0033572	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	464	Identity:	122/464 - (26%)
Similarity:	225/464 - (48%)	Gaps:	21/464 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PDGQESLPSA--PTVENPP-PYTNAINDFNSKANLTEKELSLTDDPYHPFEHRDPNGASAG-GAL 69
            |..|:..|:.  |.::..| ....:|..|..               |:|:|.|........ .|.
  Fly     3 PKSQDQAPNRDDPDLQTEPLTIAQSITSFYM---------------YNPYEKRSVEVPLTNCDAF 52

  Fly    70 AHLLKSSLGTGILAMPMAFHNAGLAFGMAMTLIVGFLCTHCVHILVKTSHDICRDAKVSALGFAE 134
            ..|||..:||||||||:||..:|...|..|::::..|.|:.:|:|:....:.||..:|..:...|
  Fly    53 ISLLKCVIGTGILAMPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRRRVPQVSMPE 117

  Fly   135 TAEKVFEYGPKGMRPYSNFAKQFVDIGLMATYYAAACVYIVFIATSFHDVINYDLKINWDVRIYI 199
            .....:|.|||.:..:...|.......|:...:....||:||::.:|.::.::.:: .::.|.|:
  Fly   118 AVRIAYEEGPKWINCFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDHYIE-RYNERYYV 181

  Fly   200 ALTVIPCLLIGQIRDLKWLVPFSMMANIFIVVTFAITLYYMFDEPLVYSDKPLIAKAAHIPLFFA 264
            .:..:..|.:..||.||:|||.::::|..:...||:.:||:|:.....:|:.::........|.|
  Fly   182 LVACLLLLPLFMIRRLKYLVPLNLISNFLLYAGFALIMYYLFNGLPNINDREMVTPPVEWIEFIA 246

  Fly   265 TVIFAMEGIGVVMPVENSMRKPQHFLGCPGVLNIAMVTVVSLYAIIGFFGYVRFGDQVRGSITLN 329
            ...|::..:|.::.||..|..||.:||..||||:|::.::......|..||.||||.|..|||||
  Fly   247 IAAFSLTAVGSMLVVEAHMAHPQSYLGLFGVLNLAVLFILLSNMFFGIIGYWRFGDNVHASITLN 311

  Fly   330 LPEGAWLGDTAKLLMAVAILFTFGLQFYVPNEILWRKISHKFSPEKH-NITQILLRSGIILLSGG 393
            :|:...|....|:.:|..|..::.|..:|...:::....:.....:: .:.:.::|...:.|:|.
  Fly   312 IPQDEILSQFIKVFIASGIFLSYPLNGFVVITVMFSDYENSEPRGRYRTLIEYVVRLLFLFLTGA 376

  Fly   394 VAAAIPNLEPFISLVGAVFFSLLGIFVPSFVETVYLWPDRLGVCKWKLVKNIFLGVFSILALVAG 458
            ||..:|||.....|.||...|.|.:..|:.::....:....|...|||:::|.|.:..::..:.|
  Fly   377 VAIGVPNLAALTELEGAFSLSNLNLLCPALIDVFLNYNVGYGRLMWKLIRDILLILIGLIFGIVG 441

  Fly   459 AVASINEII 467
            ...::.::|
  Fly   442 CTVALMQLI 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	109/398 (27%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	110/402 (27%)
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	103/357 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	157	1.000	Domainoid score	I1306
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1622
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm1178
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
	9	8.970