DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8785 and Slc36a4

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001101597.1	Gene:	Slc36a4 / 315439	RGDID:	1311528	Length:	500	Species:	Rattus norvegicus

Alignment Length:	461	Identity:	155/461 - (33%)
Similarity:	240/461 - (52%)	Gaps:	28/461 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PYTNAINDFNSKANLTEKELSLTDDPYHPFEHRDPNGASAGGALAHLLKSSLGTGILAMPMAFHN 90
            |..|..| |:..:: .|:|.:|.....| ::....:|.|....|.||||.::|||:|.:|:|..|
  Rat    22 PLINEQN-FDGSSD-EEQEQTLLPMQKH-YQLDGQHGISFVQTLMHLLKGNIGTGLLGLPLAIKN 83

  Fly    91 AGLAFGMAMTLIVGFLCTHCVHILVKTSHDICRDAKVSALGFAETAEKVFEYGP-KGMRPYSNFA 154
            ||:..|....:.:|.:..||:||||:.||.:|:..|.|.||:::|.....|..| ..::..:.:.
  Rat    84 AGIVLGPISLVFIGIISVHCMHILVRCSHFLCQRFKKSTLGYSDTVSFAMEASPWSCLQRQAAWG 148

  Fly   155 KQFVDIGLMATYYAAACVYIVFIATSFHDV------------INYDL-----KINWDVRIYIALT 202
            :..||..|:.|......|||||:|.:...|            .:.||     :.:.|:|:|: |.
  Rat   149 RSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGLLETTVVVSNSSDLSQVCERRSVDLRVYM-LC 212

  Fly   203 VIPCL-LIGQIRDLKWLVPFSMMANIFIVVTFAITLYYMFDEPLVYSDKPLIAKAAHIPLFFATV 266
            .:|.| |:..||:||.|...|.:|||.:..:..|...|:........:.|::|.....||||.|.
  Rat   213 FLPLLILLVFIRELKSLFVLSFLANISMAASLVIIYQYVVRSMPDPHNLPIVAGWKKYPLFFGTA 277

  Fly   267 IFAMEGIGVVMPVENSMRKPQHFLGCPGVLNIAMVTVVSLYAIIGFFGYVRFGDQVRGSITLNLP 331
            :||.||||||:|:||.||:.:.|   |..|||.|..|..||..:...||:.|.|:::||||||||
  Rat   278 VFAFEGIGVVLPLENQMRESKRF---PQALNIGMAIVTVLYISLATLGYMCFRDEIKGSITLNLP 339

  Fly   332 EGAWLGDTAKLLMAVAILFTFGLQFYVPNEILWRKISHKFSPEKHNITQILLRSGIILLSGGVAA 396
            :..||..:.|:|.:..|..|:.:|||||.||:...::.:...:...|....:||.::.::...|.
  Rat   340 QDMWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPAVTARLHAKWKCICDFGIRSLLVSITCAGAV 404

  Fly   397 AIPNLEPFISLVGAVFFSLLGIFVPSFVETVYLWPDRLGVCKWKLVKNIFLGVFSILALVAGAVA 461
            .||.|:..||.||||..|.|.:.:|..||.:....|...|  |.::|||.:.....:..:.|...
  Rat   405 LIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKDHYNV--WMVLKNISIAFTGFVGFLLGTYV 467

  Fly   462 SINEII 467
            ::.|||
  Rat   468 TVEEII 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	143/415 (34%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	144/419 (34%)
Slc36a4	NP_001101597.1	SLC5-6-like_sbd	54..469	CDD:294310	144/420 (34%)
Slc36a4	NP_001101597.1	PotE	<223..477	CDD:223605	93/256 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.930