DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8785 and Slc36a3

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001019935.1	Gene:	Slc36a3 / 303148	RGDID:	1309092	Length:	477	Species:	Rattus norvegicus

Alignment Length:	414	Identity:	130/414 - (31%)
Similarity:	213/414 - (51%)	Gaps:	24/414 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 HLLKSSLGTGILAMPMAFHNAGLAFGMAMTLIVGFLCTHCVHILVKTSHDICRDAKVSALGFAET 135
            |||||::|||.|.:|:|..||||..|....|.:|.|..||:.||:..:..:....:.|.:.:.||
  Rat    58 HLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTSRLQRSFVNYEET 122

  Fly   136 AEKVFEYGPK-GMRPYSNFAKQFVDIGLMATYYAAACVYIVFIATSFHDVI-------------- 185
            .....|..|. .:|.:|.:.:..|...|:.|......||.:|:|.:...::
  Rat   123 TMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFMADNLQQIVEEAHFTSNVCQPRQ 187

  Fly   186 NYDLKINWDVRIYIALTVIPCL-LIGQIRDLKWLVPFSMMANIFIVVTFAITLYYMFDEPLVYSD 249
            :..:....|.|.|: ||::|.| |:..:::.:.|..||.:|.|..:.:.|:...|:...| .:|.
  Rat   188 SLVMTSILDTRFYM-LTILPFLILLVLVQNPQVLSIFSTLATITTLSSLALIFEYLIQIP-HHSH 250

  Fly   250 KPLIAKAAHIPLFFATVIFAMEGIGVVMPVENSMRKPQHFLGCPGVLNIAMVTVVSLYAIIGFFG 314
            .||:|......|||.|.||..||:|:|:|:::.|:.||.|   |.||.:.|..|:.||..:|..|
  Rat   251 LPLVASWKTFLLFFGTAIFTFEGVGMVLPLKSQMKSPQQF---PAVLYLGMSFVIFLYICLGTLG 312

  Fly   315 YVRFGDQVRGSITLNLPEGAWLGDTAKLLMAVAILFTFGLQFYVPNEILWRKISHKFSPEKHNIT 379
            |::||...:.||||||| ..||..:.||:.:|.|.||:.|||:||.||:...:..:.|.......
  Rat   313 YMKFGADTQASITLNLP-NCWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPYVVSRASENWALFI 376

  Fly   380 QILLRSGIILLSGGVAAAIPNLEPFISLVGAVFFSLLGIFVPSFVETVYLWPDRLGVCKWKLVKN 444
            .:.:|:.::.|:...|..||.|:..|||||:|..|.|.:.:|..:|....:.:.:. |. .:.|:
  Rat   377 DLTVRAALVCLTCFSAVLIPRLDLVISLVGSVSSSALALIIPPLLEIATFYSENIS-CT-TIAKD 439

  Fly   445 IFLGVFSILALVAGAVASINEIIE 468
            |.:.:..:|..|.|...::.|:.:
  Rat   440 IMISILGLLGCVLGTYQALYEMTQ 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	127/401 (32%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	129/407 (32%)
Slc36a3	NP_001019935.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
Slc36a3	NP_001019935.1	SLC5-6-like_sbd	52..458	CDD:294310	129/407 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.930