DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8785 and Slc38a6

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001013117.1	Gene:	Slc38a6 / 299139	RGDID:	1310330	Length:	457	Species:	Rattus norvegicus

Alignment Length:	495	Identity:	113/495 - (22%)
Similarity:	201/495 - (40%)	Gaps:	123/495 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 NLTEKELSLTDDPYHPFEHRDP-----NGASAGGALAHLLKSSLGTGILAMPMAFHNAGLAFGMA 98
            ::.:.|.::..:.:.|....:|     :|||.|.::.:::.:.:|:|||.:.....|.|:.....
  Rat    17 SVQQPEEAVAAEEWSPLLSNEPRRQGSSGASFGLSVFNVMNAIMGSGILGLAYVMANTGILGFSF 81

  Fly    99 MTLIVGFLCTHCVHILVKTSHDICRDAKVSA---LGFAETAEKVFEYGPKGMRPYSNFAKQFV-- 158
            :.|:|..|.::.||:|:.    :|....|::   ||       :|.:|..|        |..|
  Rat    82 LLLLVALLASYSVHLLLA----MCIHTAVTSYEDLG-------LFAFGLPG--------KVVVAG 127

  Fly   159 -----DIGLMATY-------------------YAAA------------CVYIVFIATSFHDV--I 185
                 :||.|::|                   ::.|            ||.|||..:....:  :
  Rat   128 TIIIQNIGAMSSYLLIIKTELPAAISEVLPSDHSGAWYLDGQMLLIIICVGIVFPLSLLPKIGFL 192

  Fly   186 NYDLKINWDVRIYIALTVIPCLLIGQIRDLKWLVPFSMMANIFIVVTFAIT---------LYYMF 241
            .|...:::...::.||.|:       |:  ||.||..:..|. |...|.|:         |:: |
  Rat   193 GYTSSLSFFFMVFFALVVV-------IK--KWAVPCPLTLNC-INAVFQISNATDDCKPKLFH-F 246

  Fly   242 DEPLVYSDKPLIAKAAHIPLFFATVIFAMEGIGVVMPVENSMRKPQHFLGCPGVLNIAMVTVVSL 306
            .:..||:          ||    |:.|:......|:|:...:|.|.. .....|.|.|:.....:
  Rat   247 SKESVYA----------IP----TMAFSFLCHTSVLPIYCELRSPSK-KRMQNVTNTAIALSFLV 296

  Fly   307 YAIIGFFGYVRFGDQVRGSI----TLNLPEGAWLGDTAKLLMAVAILFTFGLQFYVPNEILWRKI 367
            |.:...|||:.|.|:|...:    :..||..|.: ...||.:..|:|.|..|..:...:.|...:
  Rat   297 YFVSALFGYLTFYDKVESELLQGYSKYLPHDAAV-MAVKLCILFAVLLTVPLIHFPARKALMMIL 360

  Fly   368 --SHKFSPEKHNITQILLRSGIILLSGGVAAAIPNLEPFISLVGAVFFSLLGIFVPSFVETVYLW 430
              ::.||..:|::|.:.|...|:||    |..:|::.....:|||...:.| |||  |....||.
  Rat   361 FSNYPFSWIRHSLTTLALNIIIVLL----AIYVPDIRNVFGVVGASTSTCL-IFV--FPGLFYLK 418

  Fly   431 PDRLGVCKWKLVKNIFLGVFSILA--LVAGAVASINEIIE 468
            ..|.....||.     ||..|:|:  .|.|:.:.:..|::
  Rat   419 LSREDFLSWKK-----LGALSLLSTGTVVGSFSLVLIILD 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	108/461 (23%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	109/460 (24%)
Slc38a6	NP_001013117.1	SLC5-6-like_sbd	45..452	CDD:294310	109/464 (23%)
Slc38a6	NP_001013117.1	SdaC	45..447	CDD:223884	109/459 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910