DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8785 and Slc38a2

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	XP_006242344.1	Gene:	Slc38a2 / 29642	RGDID:	69420	Length:	535	Species:	Rattus norvegicus

Alignment Length:	570	Identity:	108/570 - (18%)
Similarity:	210/570 - (36%)	Gaps:	172/570 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DNKGFTPDGQESLPSAPT---------VENPPPYTNAINDFNSKANLTEKELSLTDDPYHPFEHR 58
            |:..::.:|..:. |.||         |:..|...|    |..::||.:|:.. ||  :|
  Rat    16 DSSSYSSNGDFNY-SYPTKQAALKSHYVDVDPENQN----FLLESNLGKKKYE-TD--FH----- 67

  Fly    59 DPNGASAGGALAHLLKSSLGTGILAMPMAFHNAGLAFGMAMTLIVGFLCTHCVHILVKTSHDICR 123
             |...|.|.::.:|..:.:|:|||.:..|..|.|:|..:.:...|.....:.||:|:||:::
  Rat    68 -PGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANE--- 128

  Fly   124 DAKVSALGFAETAEKVFEYGPKGMRPYSNFAKQFVDIGLMATYYAAACVYIVFIATSFHDVINYD 188
               ..:|.:.:...|.  ||..|....|. :....:||.|::|        :||       :.|:
  Rat   129 ---GGSLLYEQLGHKA--YGLAGKLAASG-SITMQNIGAMSSY--------LFI-------VKYE 172

  Fly   189 LK-----------------INWDVRIYIA--LTVIPCLLIGQIRDLKWLVPFSMMANIFIVVTFA 234
            |.                 :|.|..:.:.  :.::|..|:..:..|.:....|::..||.::...
  Rat   173 LPLVIKALMNIEDTNGLWYLNGDYLVLLVSFVLILPLSLLRNLGYLGYTSGLSLLCMIFFLIVVG 237

  Fly   235 ITLYYMFDEPLVYSDKPLIAKA--AHIPLFFATVIFAMEGI----GVVMPVENSMR--------- 284
            :         :|:..:..|.||  .| |....:.||..:.|    .:..|||.::.
  Rat   238 V---------VVFVCRKCILKALSGH-PALLTSAIFCCQVICKKFQIPCPVEVALMANETVNGTF 292

  Fly   285 ------------------KPQHFL----------------GC-PGVL---------------NIA 299
                              :|::|:                .| |.||               |::
  Rat   293 TQVALAALASNSTAADTCRPRYFIFNSQTVYAVPILTFSFVCHPAVLPIYEELKSRSRRRMMNVS 357

  Fly   300 MVTVVS---LYAIIGFFGYVRFGDQVRGSITLNLPEGAWLGDTAKLLMAVAILFTFGLQFYVPNE 361
            .::..:   :|.:...|||:.|.:.|...:   |...:.:..|..||:.|.:.....:...||..
  Rat   358 KISFFAMFLMYLLAALFGYLTFYEHVESEL---LHTYSAIVGTDILLLVVRLAVLVAVTLTVPVV 419

  Fly   362 I--LWRKISHKFSPEK------HNITQILLRSGIILLSGGVAAAIPNLEPFISLVGAVFFSLLGI 418
            |  :...::|...|.|      |::..:.    |:..:..:...:|.:......:||...::|..
  Rat   420 IFPIRSSVTHLLCPTKEFSWFRHSVITVT----ILAFTNLLVIFVPTIRDIFGFIGASAAAMLIF 480

  Fly   419 FVPS--FVETVYLWPDRLGVCKWKLVKNIFLGVFSILALVAGAVASINEI 466
            .:||  :::.|...|.| .|.|          :.::..|::|.|..|..:
  Rat   481 ILPSAFYIKLVKKEPMR-SVQK----------IGALCFLLSGVVVMIGSM 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	90/493 (18%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	91/497 (18%)
Slc38a2	XP_006242344.1	SdaC	64..516	CDD:223884	95/511 (19%)
Slc38a2	XP_006242344.1	SLC5-6-like_sbd	69..518	CDD:294310	92/500 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910