DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8785 and avt3

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_593551.1	Gene:	avt3 / 2543612	PomBaseID:	SPAC3H1.09c	Length:	656	Species:	Schizosaccharomyces pombe

Alignment Length:	435	Identity:	110/435 - (25%)
Similarity:	186/435 - (42%)	Gaps:	83/435 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 FEHRDPNGASAGGALAHLLKSSLGTGILAMPMAFHNAGLAFGMAMTLIVGFLCTHCVHILVKTSH 119
            ::.:.|..||.|.|:..||||.:|||:|.:|.||...||.|..|..||||.|...|..:|::|.
pombe   267 YKLQTPGNASNGKAVLLLLKSFVGTGVLFLPKAFKLGGLVFSSATLLIVGVLSHICFLLLIQTR- 330

  Fly   120 DICRDAKVSALGFAETAEKVFEYGPKGMRPYSNFAKQFVDIGLMATYYAAACVYIVFIATSFHDV 184
                 .||.. .|.:....:  ||     |:..||   :...::.:....:..||.|:|::....
pombe   331 -----MKVPG-SFGDIGGTL--YG-----PHMRFA---ILASIVVSQIGFSSAYISFVASTLQAC 379

  Fly   185 INYDLKI------NWDVRIYIALTVIPCLLIGQIRDLKWLVPFSMMANIFIVVTFAITLYYMFDE 243
            :    |:      .:.:.::|.:..:..:.:..:|.:..|...:::|::||::..   ||..|.:
pombe   380 V----KVISTTHREYHLAVFIFIQFLVFVPLSLVRKISKLSATALIADVFILLGI---LYLYFWD 437

  Fly   244 PLVYSDKPLIAKA----AHIPLFFATVIFAMEGIGVVMPVENSMRKPQHFLGCPGVLNIAMVTVV 304
            .:..:.|.:...|    ....||....||..|||.:::|::..|.||::.   |.:|...|..:.
pombe   438 VITLATKGIADVAMFNKTDFSLFIGVAIFTYEGICLILPIQEQMAKPKNL---PKLLTGVMAAIS 499

  Fly   305 SLYAIIGFFGYVRFGDQVRGSITLNLPEGAWLGDTAKLLMAVAILFTFGLQFYVP---------- 359
            .|:..||...|..||.:|:..:.||:||..:. ...:.|.|:|||.:..||.:..
pombe   500 LLFISIGLLSYAAFGSKVKTVVILNMPESTFT-VIIQFLYAIAILLSTPLQLFPAIAIIEQGIFT 563

  Fly   360 ------NEILWRKISHKFSPEKHNITQILLRSGIILLSGGVAAAIPNLEPFISLVGAVFFSLLGI 418
                  .:|.|||          |..::|:....||:|.   |....|:.|:|:||:|
pombe   564 RSGKRNRKIKWRK----------NYLRVLIVILAILISW---AGSSRLDLFVSMVGSV------- 608

  Fly   419 FVPSFVETVYLWPDRL--GVCKWKLVKNIFLGVFSILALVAGAVA 461
               ..:..:|::|..|  ..|    ..|..|....|.....||.|
pombe   609 ---CCIPLIYMYPPMLHYKAC----ANNWILRTLDIFMFTIGAFA 646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	107/424 (25%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	109/428 (25%)
avt3	NP_593551.1	SdaC	270..656	CDD:223884	110/432 (25%)
avt3	NP_593551.1	Aa_trans	273..656	CDD:279788	109/429 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	126	1.000	Domainoid score	I1377
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	126	1.000	Inparanoid score	I1449
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		otm47069
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
TreeFam	0	0.000	Not matched by this tool.
	8	7.860