DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8785 and Slc36a2

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_694810.2	Gene:	Slc36a2 / 246049	MGIID:	1891430	Length:	478	Species:	Mus musculus

Alignment Length:	477	Identity:	149/477 - (31%)
Similarity:	241/477 - (50%)	Gaps:	43/477 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TPDGQESLPSAPTVENPPPYTNAINDFNSKANLTEKELSLTDDPYHPFEHRDPNGASAGGALAHL 72
            ||...:...||..:::..|         |.||.:..|.|           :...|.:....|.||
Mouse    14 TPLNLDLPESAKKLQSQDP---------SPANGSSSESS-----------KKTKGITGFQTLVHL 58

  Fly    73 LKSSLGTGILAMPMAFHNAGLAFGMAMTLIVGFLCTHCVHILVKTSHDICRDAKVSALGFAETAE 137
            :|.::|||||.:|:|..|||:..|....|::|.:..||:||||:.:...|.......:.:.:|..
Mouse    59 VKGNMGTGILGLPLAVKNAGILMGPLSLLVMGLIACHCMHILVRCAQRFCHRLNKPFMDYGDTVM 123

  Fly   138 KVFEYGPKG-MRPYSNFAKQFVDIGLMATYYAAACVYIVFIATSFHDVI--------------NY 187
            ....:.|.. ::.::::.::.|...|:.|.....||||||:|.:...|:              ..
Mouse   124 HGLAFSPNAWLQNHAHWGRRVVSFFLIVTQLGFCCVYIVFLADNLKQVVEAVNSTTISCHKNETV 188

  Fly   188 DLKINWDVRIYIALTVIPCL-LIGQIRDLKWLVPFSMMANIFIVVTFAITLYYMFDEPLVYSDKP 251
            .|....|.|:|: |:.:|.| |:..:|:|:.|..||::|||.::|:..|...|:..|....|..|
Mouse   189 VLTPTMDSRLYM-LSFLPVLGLLVFVRNLRVLTIFSLLANISMLVSLVIIAQYIIQEIPDASQLP 252

  Fly   252 LIAKAAHIPLFFATVIFAMEGIGVVMPVENSMRKPQHFLGCPGVLNIAMVTVVSLYAIIGFFGYV 316
            |:|.....||||.|.||:.|.||||:|:||.|:..:   |.|.:|::.|..:.:||..||..||:
Mouse   253 LVASWKTYPLFFGTAIFSFESIGVVLPLENKMKDAR---GFPTILSLGMSIITTLYIAIGALGYL 314

  Fly   317 RFGDQVRGSITLNLPEGAWLGDTAKLLMAVAILFTFGLQFYVPNEILWRKISHKFSPEKHNITQI 381
            ||||.::.||||||| ..||..:.|||..|.||.|:.||||||.||:......:.|........:
Mouse   315 RFGDDIKASITLNLP-NCWLYQSVKLLYVVGILCTYALQFYVPAEIIIPLAVSQVSKRWALPVDL 378

  Fly   382 LLRSGIILLSGGVAAAIPNLEPFISLVGAVFFSLLGIFVPSFVETVYLWPDRLGVCKWKLVKNIF 446
            .:|..::.|:..:|..||.|:..:||||:|..|.|.:.:|..:|.|..:.:  |:....:.|:..
Mouse   379 SIRLALVCLTCMLAILIPRLDLVLSLVGSVSSSALALIIPPLLEVVTYYGE--GISPLTVTKDAL 441

  Fly   447 LGVFSILALVAGAVASINEIIE 468
            :.:...:..|.|...:::|:|:
Mouse   442 ISILGFMGFVVGTYQALDELIK 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	135/412 (33%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	137/416 (33%)
Slc36a2	NP_694810.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..46		10/51 (20%)
Slc36a2	NP_694810.2	SLC5-6-like_sbd	48..458	CDD:294310	137/416 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm8749
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.930