DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8785 and Slc36a1

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_569099.1	Gene:	Slc36a1 / 155205	RGDID:	619801	Length:	475	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	159/473 - (33%)
Similarity:	244/473 - (51%)	Gaps:	60/473 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LTDDPYHPFEHRD--PNGASAGG----------------------ALAHLLKSSLGTGILAMPMA 87
            |.::.||.:...|  |..:.:.|                      .|.||||.::|||:|.:|:|
  Rat     6 LRNEDYHDYSSTDVSPEESPSEGLGSFSPGSYQRLGENSSMTWFQTLIHLLKGNIGTGLLGLPLA 70

  Fly    88 FHNAGLAFGMAMTLIVGFLCTHCVHILVKTSHDICRDAKVSALGFAETAEKVFEYGPK-GMRPYS 151
            ..||||..|....|::|.:..||:.||||.:|.:||......|.:.:|.....|..|. .:|.:|
  Rat    71 VKNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRLNKPFLDYGDTVMYGLECSPSTWIRNHS 135

  Fly   152 NFAKQFVDIGLMATYYAAACVYIVFIATSFHDVI-----------NYDLKI---NWDVRIYIALT 202
            ::.::.||..|:.|.....|||.||:|.:|..||           |.:..|   ..|.|:|: ||
  Rat   136 HWGRRIVDFFLVVTQLGFCCVYFVFLADNFKQVIEAANGTTTNCNNNETVILTPTMDSRLYM-LT 199

  Fly   203 VIPCL-LIGQIRDLKWLVPFSMMANIFIVVTFAITLYYMF-----DEPLVYSDKPLIAKAAHIPL 261
            .:|.| |:..||:|:.|..||::|||.:.|  ::.:.|.|     .:|   |..||:|.....||
  Rat   200 FLPFLVLLSFIRNLRILSIFSLLANISMFV--SLIMIYQFIVQRIPDP---SHLPLVAPWKTYPL 259

  Fly   262 FFATVIFAMEGIGVVMPVENSMRKPQHFLGCPGVLNIAMVTVVSLYAIIGFFGYVRFGDQVRGSI 326
            ||.|.|||.||||||:|:||.|:..|.|   |.:|.:.|..:..||..:|..||::||..::|||
  Rat   260 FFGTAIFAFEGIGVVLPLENKMKDSQKF---PLILYLGMAIITVLYISLGSLGYLQFGADIKGSI 321

  Fly   327 TLNLPEGAWLGDTAKLLMAVAILFTFGLQFYVPNEILWRKISHKFSPEKHN-ITQILLRSGIILL 390
            ||||| ..||..:.|||.::.|.||:.|||||..||:...|..:. ||:.. :..:..|:.::.:
  Rat   322 TLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVAAEIIIPAIVSRV-PERFELVVDLSARTAMVCV 384

  Fly   391 SGGVAAAIPNLEPFISLVGAVFFSLLGIFVPSFVETVYLWPDRLGVCKWKLVKNIFLGVFSILAL 455
            :..:|..||.|:..|||||:|..|.|.:.:|..:|....:.:  |:....:.|:..:.:...:..
  Rat   385 TCVLAVLIPRLDLVISLVGSVSSSALALIIPPLLEVTTYYGE--GISPLTITKDALISILGFVGF 447

  Fly   456 VAGAVASINEIIE-MYSD 472
            |.|...|:.|:|: .:||
  Rat   448 VVGTYESLWELIQPSHSD 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	148/440 (34%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	149/444 (34%)
Slc36a1	NP_569099.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32		6/25 (24%)
Slc36a1	NP_569099.1	SLC5-6-like_sbd	47..452	CDD:382020	148/417 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.930