DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8785 and Slc38a1

DIOPT Version :9

Sequence 1:	NP_610804.1	Gene:	CG8785 / 36391	FlyBaseID:	FBgn0033760	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001159928.1	Gene:	Slc38a1 / 105727	MGIID:	2145895	Length:	485	Species:	Mus musculus

Alignment Length:	505	Identity:	103/505 - (20%)
Similarity:	196/505 - (38%)	Gaps:	115/505 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DNKGFTPDGQESLPSAPTVENPPPYTNAINDFNSKANLTEKELSLTD-DPYHPFEHRDPNGASAG 66
            |:..||           .|||....:..|:|..|:.:||...|.... |.|      .|...|.|
Mouse    27 DSNDFT-----------EVENGQINSKFISDRESRRSLTNSHLEKRKCDEY------IPGTTSLG 74

  Fly    67 GALAHLLKSSLGTGILAMPMAFHNAGLAFGMAMTLIVGFLCTHCVHILVKTSHDICRDAKVSALG 131
            .::.:|..:.:|:|||.:..|..|.|:...:.:...|..|..:.:::|:     || ..:...:.
Mouse    75 MSVFNLSNAIMGSGILGLAFALANTGILLFLILLTSVTLLSIYSINLLL-----IC-SKETGCMV 133

  Fly   132 FAETAEKVFEYGPKGMRPYSNFAKQFVDIGLMATYYAAACV-YIVFIATSFHDVI-----NYDLK 190
            :.:..|:||  |..|         :.|..|..:.....|.: |:..:.......|     ..|..
Mouse   134 YEKLGEQVF--GTTG---------KLVIFGATSLQNTGAMLSYLFIVKNELPSAIKSLMGEEDAF 187

  Fly   191 INW--DVRIYIALT----VIPCLLIGQIRDLKWLVPFSMMANIFIVVTFAITLYYMFDEPLVYSD 249
            ..|  |.|:.:.:.    ::|..|:..:..|.:...||:...:|.::   :.:|..|..|.:..:
Mouse   188 SAWYVDGRVLVVMVTFGIILPLCLLKNLGYLGYTSGFSLSCMMFFLI---VVIYKKFQTPCMSVE 249

  Fly   250 KPLIAKA----AHIPLF----------FATVIFAMEGIGVVMPV-----ENSMRKPQHFLGCPGV 295
            :.....|    |..|.:          ..|:.||......|:|:     :.|.:|.|.      |
Mouse   250 QNSTVSANVTDACTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQM------V 308

  Fly   296 LNIAMVTVVSLYAIIGFFGYVRFGDQVRGSITLNLPEGAWLGD----TAKLLMAVAILFTFGLQF 356
            .||:...:..:|.:...|||:.|.::|:..:   |.:....||    |.:|.:.||::.|..:.|
Mouse   309 SNISFFAMFVMYFLTAIFGYLTFYEKVQSDL---LHKYQSTGDILILTVRLAVIVAVILTVPVLF 370

  Fly   357 YVPNEILWRKISH-KFSPEKHNITQILLRSGIILLSGGVAAAIPNLEPFISLVGAVFFSLLGIFV 420
            :.....|:..... ||...:|.:..|:|    :::...:...||:::....:||....::|...:
Mouse   371 FTVRSSLFELAKKTKFHLCRHVLVTIIL----LIIINLLVIFIPSMKDIFGVVGVTSANMLIFIL 431

  Fly   421 PSFVETVYLWPDRLGVCKWKLVKN------------IFLG---VFSILAL 455
            ||   ::||          |:...            :|||   :||::::
Mouse   432 PS---SLYL----------KITNQDGDKGTQRIWAALFLGLGVLFSLISI 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8785	NP_610804.1	SdaC	60..457	CDD:223884	89/447 (20%)
CG8785	NP_610804.1	SLC5-6-like_sbd	62..463	CDD:294310	88/445 (20%)
Slc38a1	NP_001159928.1	SLC5-6-like_sbd	69..472	CDD:382020	88/446 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820