DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Iswi and CHR1

DIOPT Version :9

Sequence 1:	NP_523719.1	Gene:	Iswi / 36390	FlyBaseID:	FBgn0011604	Length:	1027	Species:	Drosophila melanogaster
Sequence 2:	NP_201476.1	Gene:	CHR1 / 836808	AraportID:	AT5G66750	Length:	764	Species:	Arabidopsis thaliana

Alignment Length:	708	Identity:	254/708 - (35%)
Similarity:	400/708 - (56%)	Gaps:	88/708 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EENSNETTSDAATSSSGEKEAEFDNKIEADRSRRFDFLLKQTEIFTHFMTNSAKSPT-------K 70
            ||.:|...|..|.:.:   |.:|         .:.|.||.||::::.|:....:..|       .
plant    81 EEKANNAGSAVAPNLN---ETQF---------TKLDELLTQTQLYSEFLLEKMEDITINGIESES 133

  Fly    71 PKGRPKKIKDKDKEKDVADHRHRKTEQ---------EEDEELLAEDSATKEI---FRFDASPAYI 123
            .|..|:|.....|.|..:.:.:.|.::         :||.|.:..|...:|.   .:.:..| .:
plant   134 QKAEPEKTGRGRKRKAASQYNNTKAKRAVAAMISRSKEDGETINSDLTEEETVIKLQNELCP-LL 197

  Fly   124 KSGEMRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYLKHFKNQA--GPHIVIVPK 186
            ..|:::.||::|:.|:|||::||:||||||:||||||:|||   |:|.|.|...  ||::||.|.
plant   198 TGGQLKSYQLKGVKWLISLWQNGLNGILADQMGLGKTIQTI---GFLSHLKGNGLDGPYLVIAPL 259

  Fly   187 STLQNWVNEFKKWCPSLRAVCLIGDQDTRNTFIRDVLMP----GEWDVCVTSYEMCIRE-KSVFK 246
            |||.||.||..::.||:.|:...||::.|:. :|...||    .::.:.:||||:.:.: |.:.:
plant   260 STLSNWFNEIARFTPSINAIIYHGDKNQRDE-LRRKHMPKTVGPKFPIVITSYEVAMNDAKRILR 323

  Fly   247 KFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELWALLNFLLPDVFNSSE 311
            .:.|:|:||||.||:||.|.||...|:..|..|:||:|||||||||.|||:||||:|||:|.|.:
plant   324 HYPWKYVVIDEGHRLKNHKCKLLRELKHLKMDNKLLLTGTPLQNNLSELWSLLNFILPDIFTSHD 388

  Fly   312 DFDEWF-----NTNTCLGDD------ALITRLHAVLKPFLLRRLKAEVEKRLKPKKEMKIFVGLS 365
            :|:.||     |.|....::      .::::||.:|:||:|||:|.:||..|..|||:.::..::
plant   389 EFESWFDFSEKNKNEATKEEEEKRRAQVVSKLHGILRPFILRRMKCDVELSLPRKKEIIMYATMT 453

  Fly   366 KMQRDWYTKVLLKDIDVVNGAGKVE----KMRLQNILMQLRKCTNHPYLFDGAEPG----PPYTT 422
            ..|:.:...::...::...|...:.    |.:|.|:::||||..|||.|..|...|    ||.
plant   454 DHQKKFQEHLVNNTLEAHLGENAIRGQGWKGKLNNLVIQLRKNCNHPDLLQGQIDGSYLYPPV-- 516

  Fly   423 DTHLVYNSGKMAILDKLLPKLQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRN 487
             ..:|...||..:|::||.:|.....:||||||.|::|||::.|...:.:..||:||....::|.
plant   517 -EEIVGQCGKFRLLERLLVRLFANNHKVLIFSQWTKLLDIMDYYFSEKGFEVCRIDGSVKLDERR 580

  Fly   488 RQIQEFNMDNSAKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRV 552
            |||::|:.:.|:..:|:||||||||||||..||..|:||||||||||||||||.|||||.|.|.|
plant   581 RQIKDFSDEKSSCSIFLLSTRAGGLGINLTAADTCILYDSDWNPQMDLQAMDRCHRIGQTKPVHV 645

  Fly   553 FRLITESTVEEKIVERAEVKLRLDKMVIQGGRLVDNR---SNQLNKDEMLNIIRFGANQVFSSKE 614
            :||.|..::|.::::||..||:|:.:||..|:....|   |..|.::::|.:::..........:
plant   646 YRLSTAQSIETRVLKRAYSKLKLEHVVIGQGQFHQERAKSSTPLEEEDILALLKEDETAEDKLIQ 710

  Fly   615 TDITDEDIDVILERGEAKTAEQKAALDSLGESSLRTFTMDTNGEAGTSSVYQFEGEDW 672
            |||:|.|:|.:|:|.:                    .|:...||...:..:..:|..|
plant   711 TDISDADLDRLLDRSD--------------------LTITAPGETQAAEAFPVKGPGW 748

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Iswi	NP_523719.1	DBINO	<30..67	CDD:290603	8/36 (22%)
		SNF2_N	131..411	CDD:278600	125/301 (42%)
		DEXDc	148..287	CDD:238005	65/145 (45%)
		HELICc	422..553	CDD:238034	67/130 (52%)
		HAND	697..796	CDD:286232
		SANT	797..838	CDD:197842
		SANT	799..838	CDD:238096
		SLIDE	853..965	CDD:286233
CHR1	NP_201476.1	PLN03142	12..>739	CDD:215601	252/697 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0385
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D61251at2759
OrthoFinder	1	1.000	-	-		FOG0001113
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.780