DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Iswi and ASG3

DIOPT Version :9

Sequence 1:	NP_523719.1	Gene:	Iswi / 36390	FlyBaseID:	FBgn0011604	Length:	1027	Species:	Drosophila melanogaster
Sequence 2:	NP_973689.2	Gene:	ASG3 / 819106	AraportID:	AT2G44980	Length:	877	Species:	Arabidopsis thaliana

Alignment Length:	966	Identity:	293/966 - (30%)
Similarity:	432/966 - (44%)	Gaps:	206/966 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 EQEEDEELLAEDSATKEIFRFDASP----AYIKSGEMRDYQIRGLNWMISLYENGINGIL-ADEM 155
            |.|...|..||....||. :|..:|    .:..:..::.:|:.|::|:|..|..|:|.:| .|:|
plant    16 EYERRLEAAAEIILEKEA-KFSNTPPDCSEFGVTATLKPHQVEGVSWLIQKYLLGVNVVLELDQM 79

  Fly   156 GLGKTLQTISLLGYLKHFKNQAGPHIVIVPKSTLQNWVNEFKKWCPSLRAVCLIGDQ----DTRN 216
            |||||||.||.|.|||..:...||.:|:.|.|....||:|..::.|:|..:..:||:    |.|.
plant    80 GLGKTLQAISFLSYLKFRQGLPGPFLVLCPLSVTDGWVSEINRFTPNLEVLRYVGDKYCRLDMRK 144

  Fly   217 TFIRDV-------LMPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILRE 274
            :....|       .:|  :||.:|:|::.:.::....:..|:|.:||||.|:||..|.|..:|.|
plant   145 SMYDHVKKSSKGHFLP--FDVLLTTYDIALVDQDFLSQIPWQYAIIDEAQRLKNPNSVLYNVLLE 207

  Fly   275 -FKTANRLLITGTPLQNNLHELWALLNFLLPDVFNSSEDFDEWF-NTNTCL------GDDALITR 331
             |....||||||||:||||.|||||::|.:|.||.:.:.|...| .|...|      .|......
plant   208 QFLIPRRLLITGTPIQNNLTELWALMHFCMPLVFGTLDQFLSAFKETGDGLSGLDVSNDKETYKS 272

  Fly   332 LHAVLKPFLLRRLKAEVEKR----LKPKKEMKIFVGLSKMQRDWYTKVLLKDID--VVNGAGKVE 390
            |..:|..|:|||.|:.:.:.    |.|..|:.:.|.|..:|:..||.:|.|::.  :...:|...
plant   273 LKFILGAFMLRRTKSLLIESGNLVLPPLTELTVMVPLVSLQKKIYTSILRKELPGLLELSSGGSN 337

  Fly   391 KMRLQNILMQLRKCTNHPYLFDGAEPGPPYTTDTHLVYNSGKMAILDKLLPKLQEQGSRVLIFSQ 455
            ...||||::||||..:|||||.|.|| .|:....|||..|||:.:||:||.:|.:.|.|||:|||
plant   338 HTSLQNIVIQLRKACSHPYLFPGIEP-EPFEEGEHLVQASGKLLVLDQLLKRLHDSGHRVLLFSQ 401

  Fly   456 MTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFN----------MDNSAKFLFMLSTRAG 510
            ||..||||:|:...|.|:|.||||....|:|...|:.|:          :|.|..|:||:|||||
plant   402 MTSTLDILQDFMELRRYSYERLDGSVRAEERFAAIKNFSAKTERGLDSEVDGSNAFVFMISTRAG 466

  Fly   511 GLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVEEKIVERAEVKLRL 575
            |:|:||..||.||.|:.|||||:|.||:.|||||||...|....|:||.:|||.|:.|||.||:|
plant   467 GVGLNLVAADTVIFYEQDWNPQVDKQALQRAHRIGQISHVLSINLVTEHSVEEVILRRAERKLQL 531

  Fly   576 DKMVIQGGRLVDNRSNQLNKDEMLNIIRFGANQVFSSKETDITDEDIDVILERGEAKTAEQKAAL 640
            ...|:.     ||...:......|..:.||. |.|..:|  |.:|:.|      ..|..|    :
plant   532 SHNVVG-----DNMEEKEEDGGDLRSLVFGL-QRFDPEE--IHNEESD------NLKMVE----I 578

  Fly   641 DSLGESSLRTFTMDTNGEAGTSSVYQFEGEDWREKQKLNALGNWIEPPKRERK------------ 693
            .||.|                               |:.|:...:||.|.||:
plant   579 SSLAE-------------------------------KVVAIRQNVEPDKEERRFEINSSDTLLGN 612

  Fly   694 -ANYAVDAYFREALRVS-EPKAPKAPRPPKQPIVQDFQFFPPRLFELLDQEIYYFRKTVGYKVPK 756
             ::.::|:...||..:| ..|..:|.|..|                  |::|
plant   613 TSSASLDSELDEASYLSWVEKLKEAARSSK------------------DEKI------------- 646

  Fly   757 NTELGSDATKVQREEQRKIDEAEPLTEEEIQEKENLLSQGFTAWTKRDFNQFIKANEKYGRDDID 821
             .||| :...:..|...:|:.|....||          :....|....: |.:...|....||:|
plant   647 -IELG-NRKNLSEERNLRIEAARKKAEE----------KKLATWGAHGY-QSLSVEEPILPDDVD 698

  Fly   822 NIAKDVEGKTPEEVIEYNAVFWERCTELQDIER----IMGQIER----GEGKIQRRLSIKKALDQ 878
                     :..:....|.||.: ||....:..    |...::.    |.|      .:..||.:
plant   699 ---------SSSDAGSVNFVFGD-CTNPSTVSHEPAIIFSCVDDSGNWGRG------GMFDALSK 747

  Fly   879 KMSRYRAPFHQLRLQYGNNKGKNYTEIEDRFLVCMLHKLGFDKENVYEELRAAIRASPQFRFDWF 943
            ..:.....:|:.            :|.:|..| ..||.:..|..:..:..:|   :.|.    |.
plant   748 LSNTVPTAYHRA------------SEFKDLHL-GDLHLIKIDDNDDQQNTQA---SKPL----WV 792

  Fly   944 IKSRTALELQRRCNTLITLIERENIELEEKERAEKKKKAPKGSVSAGSGSASSNTP 999
            ..:.|.....||      .:.|.:|.:.:.|..     ..|.|.||...|||.:.|
plant   793 AVAVTQSYNSRR------KVPRSSISIPDLESC-----LAKASFSASQKSASLHMP 837

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Iswi	NP_523719.1	DBINO	<30..67	CDD:290603
		SNF2_N	131..411	CDD:278600	112/305 (37%)
		DEXDc	148..287	CDD:238005	57/151 (38%)
		HELICc	422..553	CDD:238034	71/140 (51%)
		HAND	697..796	CDD:286232	18/99 (18%)
		SANT	797..838	CDD:197842	6/40 (15%)
		SANT	799..838	CDD:238096	6/38 (16%)
		SLIDE	853..965	CDD:286233	18/119 (15%)
ASG3	NP_973689.2	PLN03142	38..>584	CDD:215601	220/597 (37%)
ASG3	NP_973689.2	Macro_Poa1p_like_SNF2	705..864	CDD:239447	34/171 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0385
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D61251at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820