Protein Alignment Iswi and smarcad1b

DIOPT Version :10

• Sequence 1: NP_523719.1
• Gene: Iswi / 36390
• FlyBaseID: FBgn0011604
• Length: 1027
• Species: Drosophila melanogaster
• Sequence 2: XP_005155692.3
• Gene: smarcad1b / 563175
• ZFINID: ZDB-GENE-091113-61
• Length: 955
• Species: Danio rerio
• Alignment Length: 657
• Identity: 229/657 - (34%)
• Similarity: 334/657 - (50%)
• Gaps: 104/657 - (15%)

  Fly    12 TEENSNETTSDAATSSSGEKEAEFDNKIEADRSRRFDFLLK-QTEIFTHFMTNSAKSPTKPKGRP 75
            |..:|.|..||:..|       ..:..:::|..:..:.|.| :|||...|.:.|....|...|..
Zfish   285 TYVSSEEECSDSEAS-------VVNGLLDSDSDQSEETLSKLKTEILCFFQSASVDELTLIAGCS 342

  Fly    76 KKIKDKDKE-------KDVADHRHRKTEQEED-----EELLAEDSATKEIFR------------- 115
            .|...|..|       ||:.|...|:.....:     .|:|.|....|.:..
Zfish   343 LKKAQKITELRPFKTWKDLDDAMRRRNGLSAELLAGCREVLKEREVVKGLMSKCEEISVKLIQDV 407

  Fly   116 ---FDASPAYIKSGE-------MRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYL 170
               .|..|..:...|       ::.||:.||||::.|::|.::||||||||||||:|.||.|.:|
Zfish   408 TQVMDKGPGSMTQPEILSSTFQLKPYQLIGLNWLVLLHQNKLSGILADEMGLGKTIQAISFLAHL 472

  Fly   171 KHFKNQAGPHIVIVPKSTLQNWVNEFKKWCPSLRAVCLIGDQDTRNTFIRDVL-MPGEWDVCVTS 234
            ....|. |||::.||.|||.|||.|...||||.:.:...|..|.|.....::| ...|:::.|::
Zfish   473 YQEGNH-GPHLITVPASTLDNWVRELNLWCPSFKVLVYYGSADDRKYMRYEILNQIVEYNIIVST 536

  Fly   235 YEMCI---REKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELW 296
            |.:.|   .::|:|.|....|.|.||.|.:||..|.....|.......|||:|||||||||.||.
Zfish   537 YNLAIGNSSDRSLFCKLKLEYAVFDEGHLLKNMNSLRYRHLMAINAKYRLLLTGTPLQNNLLELM 601

  Fly   297 ALLNFLLPDVFNSS-EDFDEWFNTNTCLGDDAL----ITRLHAVLKPFLLRRLKAEVEKRLKPKK 356
            :||||::|::|:|| ....:.|:..:.....:.    ||....::|||:|||:|:||.|:|..|:
Zfish   602 SLLNFIMPNMFSSSTSQIAKMFSMKSSEEQSSFERDRITHAKLIMKPFILRRVKSEVLKQLPAKE 666

  Fly   357 EMKIFVGLSKMQRDWYTKVLLKDIDVVNGAGKVEKMRLQNILMQLRKCTNHPYL----------- 410
            |...|..:|:.|::.|:.:|.|.....||    ||..|.|::|||||.:|||.|
Zfish   667 EQVEFCAMSERQQELYSALLHKLKHSSNG----EKRELTNVMMQLRKMSNHPLLHRQFYTTEKLK 727

  Fly   411 -----------FDGAEPG------------------------PPYTTDTHLVYNSGKMAILDKLL 440
                       ...|:|.                        ..|..:|.::.:|||:::|.:||
Zfish   728 AMSKLMLKEPSHRDADPALIKEDMEVLSDFELHRLCQQYSALHEYQLNTDVLLDSGKLSLLTQLL 792

  Fly   441 PKLQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFNMDNSAKFLFML 505
            ..|:|:|.||::|||.|.||||||.:.....:.|.||||.||..||...|.:||.|... |:|:|
Zfish   793 NSLKEKGDRVVLFSQFTMMLDILEVFLRHHKHRYNRLDGSTPMSDRIGLIDQFNTDQDI-FVFLL 856

  Fly   506 STRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVEEKIVERAE 570
            |||||||||||.:|:|||::|.|.||..|.||..|.||:||.|.|:|.:||::.::|:.::...|
Zfish   857 STRAGGLGINLTSANVVILHDIDCNPYNDKQAEGRCHRVGQTKTVKVIKLISKDSIEDTMLRIGE 921

  Fly   571 VKLRLDK 577
            .||:|::
Zfish   922 RKLKLEQ 928

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Iswi	NP_523719.1	PLN03142	46..967	CDD:215601	222/623 (36%)
smarcad1b	XP_005155692.3	CUE	179..215	CDD:270465
		ComEA	<329..377	CDD:441164	10/47 (21%)
		HepA	<429..926	CDD:440319	198/502 (39%)